Histone deacetylation, DNA methylation, and micro-RNAs (miRNAs) are the three main
epigenetic mechanisms that regulate gene expression. All the physiological processes …

Epigenetics refers to the study of mechanisms able to influence gene expression in a stable
and potentially heritable manner without altering the DNA sequence. These mechanisms …

Epigenetic regulation utilizes different mechanisms to convey heritable traits to progeny cells
that are independent of DNA sequence, including DNA silencing, post-translational …

Bone regeneration is a promising avenue for osteoporosis (OP) treatment. It consists of
several procedures, such as the osteogenic differentiation of mesenchymal stem cells as …

Bone turnover is sophisticatedly balanced by a dynamic coupling of bone formation and
resorption at various rates. The orchestration of this continuous remodeling of the skeleton …

Abstract Purpose of Review Epigenetic mechanisms modify gene activity in a stable manner
without altering DNA sequence. They participate in the adaptation to the environment, as …

Osteoporosis is a complex multifactorial condition of the musculoskeletal system.
Osteoporosis and osteoporotic vertebral fracture (OVF) are associated with high medical …

Osteoporosis is a complex disorder that is highly dependent on genetic and environmental
factors. The environmental factors, such as dietary habits and lifestyle, cause changes in …

Phenotypic variation in skeletal traits and diseases is the product of genetic and
environmental factors. Epigenetic mechanisms include information-containing factors, other …

This review describes the epigenetic regulation of osteoblastogenesis and
osteoclastogenesis and its future implementation in the diagnosis and treatment of …