Altered response dynamics and increased population correlation to tonal stimuli embedded in noise in aging auditory cortex

K Shilling-Scrivo, J Mittelstadt… - Journal of …, 2021 - Soc Neuroscience
Age-related hearing loss (presbycusis) is a chronic health condition that affects one-third of
the world population. One hallmark of presbycusis is a difficulty hearing in noisy …

Decreased modulation of population correlations in auditory cortex is associated with decreased auditory detection performance in old mice

K Shilling-Scrivo, J Mittelstadt… - Journal of …, 2022 - Soc Neuroscience
Age-related hearing loss (presbycusis) affects one-third of the world's population. One
hallmark of presbycusis is difficulty hearing in noisy environments. Presbycusis can be …

[HTML][HTML] Shaping the aging brain: role of auditory input patterns in the emergence of auditory cortical impairments

B Kamal, C Holman, E de Villers-Sidani - Frontiers in systems …, 2013 - frontiersin.org
Age-related impairments in the primary auditory cortex (A1) include poor tuning selectivity,
neural desynchronization, and degraded responses to low-probability sounds. These …

Aging affects adaptation to sound-level statistics in human auditory cortex

B Herrmann, B Maess, IS Johnsrude - Journal of Neuroscience, 2018 - Soc Neuroscience
Optimal perception requires efficient and adaptive neural processing of sensory input.
Neurons in nonhuman mammals adapt to the statistical properties of acoustic feature …

Linking anatomical and physiological markers of auditory system degeneration with behavioral hearing assessments in a mouse (Mus musculus) model of age-related …

A Kobrina, KM Schrode, LA Screven, H Javaid… - Neurobiology of …, 2020 - Elsevier
Age-related hearing loss is a very common sensory disability, affecting one in three older
adults. Establishing a link between anatomical, physiological, and behavioral markers of …

Age-related changes in excitatory and inhibitory intra-cortical circuits in auditory cortex of C57Bl/6 mice

B Xue, X Meng, JPY Kao, PO Kanold - Hearing research, 2023 - Elsevier
A common impairment in aging is age-related hearing loss (presbycusis), which manifests
as impaired spectrotemporal processing. Aging is accompanied by alteration in normal …

[HTML][HTML] Effects of aging and adult-onset hearing loss on cortical auditory regions

V Cardin - Frontiers in Neuroscience, 2016 - frontiersin.org
Hearing loss is a common feature in human aging. It has been argued that dysfunctions in
central processing are important contributing factors to hearing loss during older age. Aging …

[HTML][HTML] Temporal selectivity declines in the aging human auditory cortex

J Erb, LM Schmitt, J Obleser - Elife, 2020 - elifesciences.org
Current models successfully describe the auditory cortical response to natural sounds with a
set of spectro-temporal features. However, these models have hardly been linked to the ill …

Effects of aging on the response of single neurons to amplitude-modulated noise in primary auditory cortex of rhesus macaque

JA Overton, GH Recanzone - Journal of neurophysiology, 2016 - journals.physiology.org
Temporal envelope processing is critical for speech comprehension, which is known to be
affected by normal aging. Whereas the macaque is an excellent animal model for human …

A neural signature of regularity in sound is reduced in older adults

B Herrmann, B Maess, IS Johnsrude - Neurobiology of Aging, 2022 - Elsevier
Sensitivity to repetitions in sound amplitude and frequency is crucial for sound perception.
As with other aspects of sound processing, sensitivity to such patterns may change with age …