Cancers are the most studied yet the least understood of all the diseases of man. Our
ignorance about how to pragmatically control cancers results from our lack of understanding …

Clinicians have long maintained that many patients show evidence of resistance to their
cancer. The immunologist would hold that the change from a normal cell to a neoplastic cell …

The close relationship at the molecular level between cellular differentiation and neoplasia
has been evidenced by the discovery in adult individuals of fetospecific antigens and fetal …

Differentiation Potential of Cancer Cells Page 1 Chapter 3 Differentiation Potential of Cancer
Cells NORBERT E. FUSENIG, DIRK BREITKREUTZ and PETRA BOUKAMP Contents …

Why does one cell differ from another, a brain cell from a liver cell? Why do the cells of an
animal become programmed and thereafter retain their individual identity? Under normal …

Cellular oncology covers an ill-delineated set of topics, some of which overlap with the
clinical level of analysis, like 'invasiveness', others with the molecular level, like 'autocrine …

The cells in the body descend from precursors known as stem cells. Stem cells can multiply
rapidly; their progeny, after matur ing and differentiating into specialized forms, generally …

Cancer is discussed from a standpoint of a postembryonic differentiation. A differentiation
requires the interaction of an exogenous inductive stimulus with competent precursor cell …

A dominant view today in cancer research assumes that the major need for our
understanding of cancer resides in the thorough documentation of the many alterations in …

Neoplasms may be the result of the reestablishment of a phylogenetically primitive line of
cells rather than the direct result of cell alteration by environmental factors. Cells with …