[HTML][HTML] The revaluation of plant-derived terpenes to fight antibiotic-resistant infections

F Cappiello, MR Loffredo, C Del Plato, S Cammarone… - Antibiotics, 2020 - mdpi.com
The discovery of antibiotics has revolutionized the medicine and treatment of microbial
infections. However, the current scenario has highlighted the difficulties in marketing new …

[HTML][HTML] Terpene derivatives as a potential agent against antimicrobial resistance (AMR) pathogens

NA Mahizan, SK Yang, CL Moo, AAL Song, CM Chong… - Molecules, 2019 - mdpi.com
The evolution of antimicrobial resistance (AMR) in pathogens has prompted extensive
research to find alternative therapeutics. Plants rich with natural secondary metabolites are …

[HTML][HTML] Plant secondary metabolites in the battle of drugs and drug-resistant bacteria: new heroes or worse clones of antibiotics?

CL Gorlenko, HY Kiselev, EV Budanova… - Antibiotics, 2020 - mdpi.com
Infectious diseases that are caused by bacteria are an important cause of mortality and
morbidity in all regions of the world. Bacterial drug resistance has grown in the last decades …

Plant-derived antimicrobials: Insights into mitigation of antimicrobial resistance

SK Yang, LY Low, PSX Yap, K Yusoff… - Records of Natural …, 2018 - research.monash.edu
Antibiotic resistance had first been reported not long after the discovery of the first antibiotic
and has remained a major public health issue ever since. Challenges are constantly …

Antimicrobial terpenoids as a potential substitute in overcoming antimicrobial resistance

A Sharma, A Biharee, A Kumar, V Jaitak - Current Drug Targets, 2020 - ingentaconnect.com
There was a golden era where everyone thought that microbes can no longer establish
threat to humans but the time has come where microbes are proposing strong resistance …

[HTML][HTML] Biosynthesis investigations of terpenoid, alkaloid, and flavonoid antimicrobial agents derived from medicinal plants

W Huang, Y Wang, W Tian, X Cui, P Tu, J Li, S Shi… - Antibiotics, 2022 - mdpi.com
The overuse of antibiotics in the past decades has led to the emergence of a large number
of drug-resistant microorganisms. In recent years, the infection rate caused by multidrug …

[HTML][HTML] Antimicrobial diterpenes: Recent development from natural sources

P Saha, FI Rahman, F Hussain… - Frontiers in …, 2022 - frontiersin.org
Antimicrobial resistance has been posing an alarming threat to the treatment of infectious
diseases over the years. Ineffectiveness of the currently available synthetic and …

[HTML][HTML] Secondary plant metabolites as potent drug candidates against antimicrobial-resistant pathogens

K Keita, C Darkoh, F Okafor - SN Applied Sciences, 2022 - Springer
Antibiotic resistance is a major public health threat of the twenty-first century and represents
an important risk to the global economy. Healthcare-associated infections mainly caused by …

[HTML][HTML] A comprehensive review on medicinal plants as antimicrobial therapeutics: potential avenues of biocompatible drug discovery

U Anand, N Jacobo-Herrera, A Altemimi, N Lakhssassi - Metabolites, 2019 - mdpi.com
The war on multidrug resistance (MDR) has resulted in the greatest loss to the world's
economy. Antibiotics, the bedrock, and wonder drug of the 20th century have played a …

Antimicrobial compounds from natural sources

MA Hayashi, FC Bizerra, PI Da Silva Jr - Frontiers in microbiology, 2013 - frontiersin.org
Infectious diseases are one of the main causes of morbidity and mortality worldwide.
Nowadays many infections are often caused by multi-resistant microorganisms resulting in …