Macrophages, an important part of human immune system, possess a high plasticity and
heterogeneity (macrophage polarization) as classically activated macrophages (M1) and …

Macrophages can polarize into two different states (M1 and M2), which play contrasting
roles during pathogenesis or tissue damage. M1 polarized macrophages produce pro …

Macrophages can be affected by a variety of factors to change their phenotype and thus
affect their function. Activated macrophages are usually divided into two categories, M1-like …

Macrophages, as crucial cellular components of innate immunity, are characterized by
possessing high plasticity and an abnormal ability to differentiate in response to numerous …

Macrophages are crucial cells in the human body's innate immunity and are engaged in a
variety of non-inflammatory reactions. Macrophages can develop into two kinds when …

Macrophages undergo activation by pathophysiological stimuli to pro-inflammatory and
bactericidal, or wound-healing and anti-inflammatory phenotypes, termed M1 or M2 …

Macrophages are traditional innate immune cells that play critical roles in the clearance of
pathogens and the maintenance of tissue homeostasis. Accumulating evidence proves that …

As an essential component of innate immunity, macrophages have multiple functions in both
inhibiting or promoting cell proliferation and tissue repair. Diversity and plasticity are …

Macrophages as innate immune cells with great plasticity are of great interest for cell
therapy. There are two main macrophage populations–pro-and anti-inflammatory cells also …

Diversity and plasticity are two hallmarks of macrophages. M1 macrophages (classically
activated macrophages) are pro-inflammatory and have a central role in host defense …