Tumor multidrug resistance (MDR) is a phenomenon in which drug-resistant tumor cells are
resistant to multiple other unexposed antitumor drugs with different structures and targets …

Cancer represents a group of heterogeneous diseases characterized by uncontrolled
growth and spread of abnormal cells, ultimately leading to death. Nanomedicine plays a …

As of 21st century, cancer is arguably the most complex and challenging disease known to
mankind and an inevitable public health concern of this millennium. Nanotechnology …

One of the leading causes of death worldwide, in both men and women, is cancer. Despite
the significant development in therapeutic strategies, the inevitable emergence of drug …

Multi-drug resistance (MDR) in cancer cells, either intrinsic or acquired through various
mechanisms, significantly hinders the therapeutic efficacy of drugs. Typically, the reduced …

It is generally accepted that recent advances in anticancer agents have contributed
significantly to the improvement of both the disease-free survival and quality of life in cancer …

Cancer is the manifestation of multiple dysregulated cellular pathways. Treatment protocols
engaged in treating these diseases involve mainly the cell cycle regulating genes/proteins …

Multidrug resistance (MDR) has long been a major obstacle in the treatment of malignant
tumors. Combination therapy provides a viable and promising strategy to overcome MDR …

Cancer cells can develop resistance to anticancer drugs, thereby becoming tolerant to
treatment through different mechanisms. The biological mechanisms leading to the …

The ability of cancer cells to become resistant to chemotherapeutic agents is a major
challenge for the treatment of malignant tumors. Several strategies have emerged to attempt …