Newly synthesized chemicals are being introduced into the environment without undergoing
proper toxicological evaluation, particularly in terms of their effects on the vulnerable …

Developmental neurotoxicity (DNT) is a major safety concern for all chemicals of the human
exposome. However, DNT data from animal studies are available for only a small …

As industrial and societal advancements progress, an increasing number of environmental
pollutants linked to human existence have been substantiated to elicit neurotoxicity and …

Currently, the identification of chemicals that have the potential to induce developmental
neurotoxicity (DNT) is based on animal testing. Since at the regulatory level, systematic …

Due to the increasing prevalence of neurological disorders and the large number of
untested compounds in the environment, there is a need to develop reliable and efficient …

Background In light of the vulnerability of the developing brain, mixture risk assessment
(MRA) for the evaluation of developmental neurotoxicity (DNT) should be implemented …

Exposure to chemicals may pose a greater risk to vulnerable groups, including pregnant
women, fetuses, and children, that may lead to diseases linked to the toxicants' target …

Prenatal and postnatal co-exposure to multiple chemicals at the same time may have
deleterious effects on the developing nervous system. We previously showed that chemicals …

Halogenated persistent organic pollutants (POPs) like perfluorinated alkylated substances
(PFASs), brominated flame retardants (BFRs), organochlorine pesticides and …

There is considerable public concern that the majority of commercial chemicals have not
been evaluated for their potential to cause developmental neurotoxicity. Although several …