Attention-deficit/hyperactivity disorder (AD/HD) is a common pediatric behavioral disorder
associated, in part, with male preponderance and reduced regional cerebral blood flow …

Attention-deficit/hyperactivity disorder (AD/HD) is a common pediatric behavioral disorder
associated with male preponderance and reduction of regional cerebral blood flow (rCBF) …

Spontaneously hypertensive rats (SHR) show pronounced hippocampus alterations,
including low brain‐derived neurotrophic factor (BDNF) expression, reduced neurogenesis …

Proper cerebrovascular development and neurogliovascular unit assembly are essential for
brain growth and function throughout life, ensuring the continuous supply of nutrients and …

Estrogens are neuroprotective factors for brain diseases, including hypertensive
encephalopathy. In particular, the hippocampus is highly damaged by high blood pressure …

Previously, we showed that peripheral administration of 6β-hydroxytestosterone, a CYP1B1
(cytochrome P450 1B1)-generated metabolite of testosterone, promotes angiotensin II …

We have previously demonstrated that vascular endothelial growth factor (VEGF) is critical
for cerebral angiogenesis in middle-aged female rats and may play a role in the flow …

A dysfunction in the blood–brain barrier (BBB) is associated with many neurological and
metabolic disorders. Although sex steroid hormones have been shown to impact vascular …

Estrogen produces both beneficial and adverse effects on cardiovascular health via
mechanisms that remain unclear. Stroke-prone spontaneously hypertensive rats (SHRSP) …

Sex differences exist in how cerebral blood vessels function under both physiological and
pathological conditions, contributing to observed sex differences in risk and outcomes of …