Parkinson's disease (PD) is the most common motor-associated neurodegenerative
disease. Although the pathogenesis of PD is still wrapped in the mist, accumulating …

Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by
mitochondrial dysfunction and accumulation of alpha-synuclein (α-Syn)-containing protein …

The formation of oligomers and aggregates of overexpressed or mutant α-synuclein play a
role in the degeneration of dopaminergic neurons in Parkinson's disease by causing …

Parkinson's disease (PD) is a neurodegenerative disease characterized by the loss of
dopaminergic neurons in the substantia nigra and diminished dopamine content in the …

Parkinson's disease (PD) is a progressive neurogenerative movement disorder
characterized by dopaminergic cell death within the substantia nigra pars compacta (SNpc) …

α-Synuclein accumulation is implicated in the pathogenesis of neurodegenerative diseases,
including Parkinson's disease (PD). Previously, we reported that Fas-associated factor 1 …

Parkinson disease is characterized by the accumulation of aggregated α-synuclein as the
major component of the Lewy bodies. α-Synuclein accumulation in turn leads to …

Overexpression of alpha-synuclein and oxidative stress has been implicated in the neuronal
cell death in Parkinson's disease. Alpha-synuclein associates with mitochondria and …

α-Synuclein is highly associated with some neurodegeneration and malignancies.
Overexpressing wild-type or mutant α-synuclein promotes neuronal death by mitochondrial …

Accumulation of α-synuclein aggregates in the substantia nigra pars compacta is central in
the pathophysiology of Parkinson's disease, leading to the degeneration of dopaminergic …