Cardiac tissue engineering aims to create functional tissue constructs that can reestablish
the structure and function of injured myocardium. Engineered constructs can also serve as …

Successfully engineering a functional, human, myocardial pump would represent a
therapeutic alternative for the millions of patients with end-stage heart disease and provide …

Cardiac tissue engineering promises to revolutionize the treatment of patients with end‐
stage heart failure and provide new solutions to the serious problem of heart donor …

The promise of cardiac tissue engineering is in the ability to recapitulate in vitro the
functional aspects of a healthy heart and disease pathology as well as to design …

Cardiac tissue engineering offers the promise of creating functional tissue replacements for
use in the failing heart or for in vitro drug screening. The last decade has seen a great deal …

The engineering of 3-dimensional (3D) heart muscles has undergone exciting progress for
the past decade. Profound advances in human stem cell biology and technology, tissue …

Cardiac tissue engineering aims at repairing the diseased heart and developing cardiac
tissues for basic research and predictive toxicology applications. Since the first description of …

Tissue engineering is well suited for the treatment of cardiac disease due to the limited
regenerative capacity of native cardiac tissue and the loss of function associated with …

Engineered human cardiac tissues facilitate progress in regenerative medicine, disease
modelling and drug development. In this Perspective, we reflect on the most notable …

Twenty years after the initial description of a tissue engineered construct, 3-dimensional
human cardiac tissues of different kinds are now generated routinely in many laboratories …