[HTML][HTML] Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome

JA Belperio, MP Keane, MD Burdick… - The Journal of …, 2001 - Am Soc Clin Investig
Bronchiolitis obliterans syndrome (BOS) is the major limitation to survival after lung
transplantation. Acute rejection, its main risk factor, is characterized by perivascular …

Critical role for CXCR3 chemokine biology in the pathogenesis of bronchiolitis obliterans syndrome

JA Belperio, MP Keane, MD Burdick… - The Journal of …, 2002 - journals.aai.org
Bronchiolitis obliterans syndrome (BOS) is the major limitation to survival post-lung
transplantation and is characterized by a persistent peribronchiolar inflammation that …

CXCR3 and its ligands in a murine model of obliterative bronchiolitis: regulation and function

BD Medoff, JC Wain, E Seung, R Jackobek… - The Journal of …, 2006 - journals.aai.org
Lung transplantation remains the only effective therapy for patients with end-stage lung
disease, but survival is limited by the development of obliterative bronchiolitis (OB). The …

Role of CXCL9/CXCR3 chemokine biology during pathogenesis of acute lung allograft rejection

JA Belperio, MP Keane, MD Burdick… - The Journal of …, 2003 - journals.aai.org
Acute allograft rejection is a major complication postlung transplantation and is the main risk
factor for the development of bronchiolitis obliterans syndrome. Acute rejection is …

The presence of a matrix-derived neutrophil chemoattractant in bronchiolitis obliterans syndrome after lung transplantation

MT Hardison, FS Galin, CE Calderon… - The Journal of …, 2009 - journals.aai.org
Lung transplantation is a therapeutic modality frequently used in end-stage lung disease.
Unfortunately, lung transplant recipients have poor clinical outcomes, often due to the …

[HTML][HTML] Role of CXCR2/CXCR2 ligands in vascular remodeling during bronchiolitis obliterans syndrome

JA Belperio, MP Keane, MD Burdick… - The Journal of …, 2005 - Am Soc Clin Investig
Angiogenesis and vascular remodeling support fibroproliferative processes; however, no
study has addressed the importance of angiogenesis during fibro-obliteration of the allograft …

Role of complement activation in obliterative bronchiolitis post–lung transplantation

H Suzuki, ME Lasbury, L Fan, R Vittal… - The Journal of …, 2013 - journals.aai.org
Obliterative bronchiolitis (OB) post-lung transplantation involves IL-17–regulated
autoimmunity to type V collagen and alloimmunity, which could be enhanced by …

Upregulation of chemokines in bronchoalveolar lavage fluid as a predictive marker of post-transplant airway obliteration

M Reynaud-Gaubert, V Marin, X Thirion… - The Journal of heart and …, 2002 - Elsevier
BACKGROUND:: The early stage of post-transplant obliterative bronchiolitis (OB) is
characterized by an influx of inflammatory cells to the lung, among which neutrophils may …

[HTML][HTML] Epithelial clara cell injury occurs in bronchiolitis obliterans syndrome after human lung transplantation

FL Kelly, VE Kennedy, R Jain, NS Sindhwani… - American Journal of …, 2012 - Elsevier
Bronchiolitis obliterans syndrome (BOS) is a condition of progressive airflow obstruction that
affects a majority of lung transplant recipients and limits long-term posttransplant survival …

[HTML][HTML] Reprogramming alveolar macrophage responses to TGF-β reveals CCR2+ monocyte activity that promotes bronchiolitis obliterans syndrome

Z Liu, F Liao, J Zhu, D Zhou, GS Heo… - The Journal of …, 2022 - Am Soc Clin Investig
Bronchiolitis obliterans syndrome (BOS) is a major impediment to lung transplant survival
and is generally resistant to medical therapy. Extracorporeal photophoresis (ECP) is an …