Lung epithelial-mesenchymal transition (EMT) plays an important role in silicosis fibrosis.
The reverse process of EMT is mesenchymal-epithelial transition (MET), which is viewed as …

Silicosis is an incurable occupational disease, and its pathological feature is diffuse
pulmonary fibrosis. Pulmonary epithelial‐mesenchymal transition (EMT) is one of the …

Silicosis is pathologically characterized by diffused pulmonary fibrosis and abundant
deposition of extracellular matrix (ECM) components. The ECM is mainly secreted by …

Silicosis is a serious occupational disease characterized by pulmonary chronic inflammation
and progressive fibrosis. Epithelial-mesenchymal transition (EMT) of alveolar epithelial cells …

Silicosis is a kind of chronic, progressive and incurable lung fibrotic diseases with largely
unknown and complex pathogenesis and molecular mechanisms. Mounting evidence …

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease involving pulmonary injury
associated with tissue repair, dysfunction and fibrosis. Recent studies indicate that some …

Silicosis is a very serious occupational disease and it features pathological manifestations of
inflammatory infiltration, excessive proliferation of fibroblasts and massive depositions of the …

To identify potential therapeutic targets for pulmonary fibrosis induced by silica, we studied
the effects of this disease on the expression of microRNAs (miRNAs) in the lung. Rattus …

To identify microRNAs (miRNAs, miRs) with potential roles in lung fibrogenesis, we
performed genome-wide profiling of miRNA expression in lung tissues from a silica-induced …

Silicosis is a fatal pulmonary fibrotic disorder characterized by accumulation of fibroblasts
and myofibroblasts and deposition of extracellular matrix proteins. MiR-449a is a potential …