A randomized trial shows dose-frequency and genotype may determine the therapeutic efficacy of intranasal oxytocin
BackgroundThe neuropeptide oxytocin is proposed as a promising therapy for social
dysfunction by modulating amygdala-mediated social-emotional behavior. Although clinical …
dysfunction by modulating amygdala-mediated social-emotional behavior. Although clinical …
Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research
DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …
behavior have steadily increased over the last two decades, stimulating considerable …
Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity
Background Current neuroimaging perspectives on a variety of mental disorders emphasize
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …
Oxytocin enhances resting-state connectivity between amygdala and medial frontal cortex
The neuropeptide oxytocin (OXT) plays an important role in complex socio-affective
behaviours such as affiliation, attachment, stress and anxiety. Previous studies have focused …
behaviours such as affiliation, attachment, stress and anxiety. Previous studies have focused …
Oxytocin's effect on resting-state functional connectivity varies by age and sex
The neuropeptide oxytocin plays a role in social cognition and affective processing. The
neural processes underlying these effects are not well understood. Modulation of …
neural processes underlying these effects are not well understood. Modulation of …
Oxytocin-augmented psychotherapy: beware of context
R Hurlemann - Neuropsychopharmacology, 2017 - ncbi.nlm.nih.gov
The hypothalamic peptide oxytocin modulates a wide range of social and cognitive functions
in humans and nonhuman primates. As a result, much effort is currently being devoted to …
in humans and nonhuman primates. As a result, much effort is currently being devoted to …
Oxytocin differentially alters resting state functional connectivity between amygdala subregions and emotional control networks: Inverse correlation with depressive …
The hypothalamic neuropeptide oxytocin (OT) has received increasing attention for its role in
modulating social-emotional processes across species. Previous studies on using intranasal …
modulating social-emotional processes across species. Previous studies on using intranasal …
Oxytocin enhances amygdala-dependent, socially reinforced learning and emotional empathy in humans
R Hurlemann, A Patin, OA Onur, MX Cohen… - Journal of …, 2010 - Soc Neuroscience
Oxytocin (OT) is becoming increasingly established as a prosocial neuropeptide in humans
with therapeutic potential in treatment of social, cognitive, and mood disorders. However, the …
with therapeutic potential in treatment of social, cognitive, and mood disorders. However, the …
Oral oxytocin facilitates responses to emotional faces in reward and emotional-processing networks in females
Introduction: Oxytocin (OXT) is proposed as a potential therapeutic peptide for social
dysfunction due to its modulatory actions on socioemotional regulation in humans. While the …
dysfunction due to its modulatory actions on socioemotional regulation in humans. While the …
Kinetics of oxytocin effects on amygdala and striatal reactivity vary between women and men
Accumulating evidence suggests that intranasal oxytocin (OXT; 24 IU) reduces amygdala
responses to fear-related stimuli in men, while exerting inverse effects in women. However …
responses to fear-related stimuli in men, while exerting inverse effects in women. However …