The general secretion pathway (GSP) of Vibrio cholerae is required for secretion of proteins
including chitinase, enterotoxin, and protease through the outer membrane. In this study, we …

The general secretion pathway of gram-negative bacteria is responsible for extracellular
secretion of a number of different proteins, including proteases and toxins. This pathway …

Cholera toxin secretion is dependent upon the extracellular protein secretion apparatus
encoded by the eps gene locus of Vibrio cholerae. Although the eps gene locus encodes …

Biogenesis of the Vibrio cholerae toxin-coregulated pilus (TCP) requires the activities of at
least seven accessory proteins. We demonstrate that a portion of this pathway involves a …

The chiA gene of Vibrio cholerae encodes a polypeptide which degrades chitin, a
homopolymer of N-acetylglucosamine (GlcNAc) found in cell walls of fungi and in the …

The type II secretion system is a multi‐protein complex that spans the cell envelope of Gram‐
negative bacteria and promotes the secretion of proteins, including several virulence factors …

Extracellular secretion of proteins via the type II or general secretion pathway in gram-
negative bacteria requires the assistance of at least 12 gene products that are thought to …

Type II secretion systems consist of an assembly of 12–15 Gsp proteins responsible for
transporting a variety of virulence factors across the outer membrane in several pathogenic …

A gene essential for the secretion of cholera toxin from the periplasm of Vibrio cholerae into
the extracellular medium has been isolated and its nucleotide sequence determined. It …

Many Gram-negative bacteria use the multi-protein type II secretion system (T2SS) to
selectively translocate virulence factors from the periplasmic space into the extracellular …