Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions
M Raices, MA D'angelo - Nature reviews Molecular cell biology, 2012 - nature.com
Nuclear pore complexes (NPCs) are multiprotein aqueous channels that penetrate the
nuclear envelope connecting the nucleus and the cytoplasm. NPCs consist of multiple …
nuclear envelope connecting the nucleus and the cytoplasm. NPCs consist of multiple …
The nuclear pore complex–structure and function at a glance
G Kabachinski, TU Schwartz - Journal of cell science, 2015 - journals.biologists.com
Nuclear pore complexes (NPCs) are indispensable for cell function and are at the center of
several human diseases. NPCs provide access to the nucleus and regulate the transport of …
several human diseases. NPCs provide access to the nucleus and regulate the transport of …
The role of nuclear pores in gene regulation, development and disease
M Capelson, MW Hetzer - EMBO reports, 2009 - embopress.org
Nuclear‐pore complexes (NPCs) are large protein channels that span the nuclear envelope
(NE), which is a double membrane that encloses the nuclear genome of eukaryotes. Each of …
(NE), which is a double membrane that encloses the nuclear genome of eukaryotes. Each of …
The nuclear pore complex: understanding its function through structural insight
M Beck, E Hurt - Nature reviews Molecular cell biology, 2017 - nature.com
Nuclear pore complexes (NPCs) fuse the inner and outer nuclear membranes to form
channels across the nuclear envelope. They are large macromolecular assemblies with a …
channels across the nuclear envelope. They are large macromolecular assemblies with a …
Nucleoporin domain topology is linked to the transport status of the nuclear pore complex
SM Paulillo, EM Phillips, J Köser, U Sauder… - Journal of molecular …, 2005 - Elsevier
Nuclear pore complexes (NPCs) facilitate macromolecular exchange between the nucleus
and cytoplasm of eukaryotic cells. The vertebrate NPC is composed of∼ 30 different …
and cytoplasm of eukaryotic cells. The vertebrate NPC is composed of∼ 30 different …
Functional architecture of the nuclear pore complex
E Grossman, O Medalia… - Annual review of …, 2012 - annualreviews.org
The nuclear pore complex (NPC) is the sole gateway between the nucleus and the
cytoplasm. NPCs fuse the inner and outer nuclear membranes to form aqueous …
cytoplasm. NPCs fuse the inner and outer nuclear membranes to form aqueous …
Nuclear pore proteins and the control of genome functions
A Ibarra, MW Hetzer - Genes & development, 2015 - genesdev.cshlp.org
Nuclear pore complexes (NPCs) are composed of several copies of∼ 30 different proteins
called nucleoporins (Nups). NPCs penetrate the nuclear envelope (NE) and regulate the …
called nucleoporins (Nups). NPCs penetrate the nuclear envelope (NE) and regulate the …
Biology and biophysics of the nuclear pore complex and its components
Nucleocytoplasmic exchange of proteins and ribonucleoprotein particles occurs via nuclear
pore complexes (NPCs) that reside in the double membrane of the nuclear envelope (NE) …
pore complexes (NPCs) that reside in the double membrane of the nuclear envelope (NE) …
Structural analysis of the nuclear pore complex by integrated approaches
In eukaryotic cells, the nucleus is surrounded by a double membrane system, the nuclear
envelope (NE), in which the outer membrane is continuous with the endoplasmic reticulum …
envelope (NE), in which the outer membrane is continuous with the endoplasmic reticulum …
Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex
IC Berke, T Boehmer, G Blobel… - The Journal of cell biology, 2004 - rupress.org
Nucleocytoplasmic transport occurs through nuclear pore complexes (NPCs) whose
complex architecture is generated from a set of only∼ 30 proteins, termed nucleoporins …
complex architecture is generated from a set of only∼ 30 proteins, termed nucleoporins …