Production of no‐carrier‐added 64Cu from zinc metal irradiated under boron shielding

KR Zinn, TR Chaudhuri, TP Cheng, J Steven Morris… - Cancer, 1994 - Wiley Online Library
Background. Positron emission tomography offers advantages for radioimmunodiagnosis of
cancer but requires radionuclides of appropriate half‐life that have high specific activity and …

One step purification process for no-carrier-added 64Cu produced using enriched nickel target

C Alliot, N Michel, AC Bonraisin, V Bossé, J Laizé… - 2011 - degruyter.com
Copper-64 has found many applications in positron emission tomography (PET). Its half-life
allows to use it for dosimetric studies associated to copper-67 targeted radiotherapy in …

Development of a high performance zinc-62/copper-62 radionuclide generator for positron emission tomography

J Zweit, R Goodall, M Cox, JW Babich… - European journal of …, 1992 - Springer
Clinical utilisation of positron emission tomography could be enhanced by the availability of
shortlived radionuclides derived from generator systems. The zinc-62/copper-62 …

Efficient preparation of high-quality 64Cu for routine use

T Ohya, K Nagatsu, H Suzuki, M Fukada… - Nuclear Medicine and …, 2016 - Elsevier
Introduction Copper-64 is an attractive radionuclide for positron emission tomography and is
emerging as a radiotherapeutic agent. The demand of 64 Cu with low metallic impurities has …

Production of therapeutic quantities of 64Cu using a 12 MeV cyclotron

A Obata, S Kasamatsu, DW McCarthy, MJ Welch… - Nuclear medicine and …, 2003 - Elsevier
64Cu is a useful radiotracer for positron emission tomography (PET) and a promising
radiotherapy agent for the treatment of cancer. Recently, 64Cu-labeled …

Preparation and preliminary evaluation of 63Zn-zinc citrate as a novel PET imaging biomarker for zinc

TR DeGrado, MK Pandey, JF Byrne… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Abnormalities of zinc homeostasis are indicated in many human diseases. A noninvasive
imaging method for monitoring zinc in the body would be useful to understand zinc …

A new separation procedure for 67Cu from proton irradiated Zn

AK Dasgupta, LF Mausner, SC Srivastava - International journal of radiation …, 1991 - Elsevier
Cu-67 has been produced since 1985 at the Brookhaven Linac Isotope Producer (BLIP) by
irradiation of natural Zn targets with 200 MeV protons. Since the electrodeposition method …

A purification system for 64Cu produced by a biomedical cyclotron for antibody PET imaging

T Toyota, T Hanafusa, T Oda, I Koumura… - … of Radioanalytical and …, 2013 - Springer
Ion exchange is a simple and efficient method for separating no-carrier-added 64 Cu from
an irradiated Ni target. We developed a semi-automated two-round 64 Cu separation system …

Efficient production of high specific activity 64Cu using a biomedical cyclotron

DW McCarthy, RE Shefer, RE Klinkowstein… - Nuclear medicine and …, 1997 - Elsevier
Copper-64 (T 1 2= 12.7 h) is an intermediate-lived positron-emitting radionuclide that is a
useful radiotracer for positron emission tomography (PET) as well as a promising …

Implementation of a new separation method to produce qualitatively improved 64Cu

NP van der Meulen, R Hasler, A Blanc… - Journal of Labelled …, 2019 - Wiley Online Library
Background 64Cu (T1/2= 12.7 h) is an important radionuclide for diagnostic purposes and
used for positron emission tomography (PET). A previous method utilized at Paul Scherrer …