Possibly 10 years. The longest published follow-up extended five years, at which time
antibody levels and cell-mediated immunity were still readily detectable (1). The slow …

In this issue of Pediatrics, the vaccine research group at Kaiser Permanente Northern
California (KPNC) contributed another important article outlining the challenges of pertussis …

The decision to replace effective whole-cell vaccines for pertussis with less reactogenic but
potentially less efficacious acellular vaccines for the primary immunization of children in the …

During the 2010 pertussis epidemic in California, there was considerable concern in the
press and in public health communications about the possible contribution of vaccine …

Immunization against pertussis (whooping cough) has been part of the routine childhood
immunization program for over 50 years. Until 1997, a whole cell pertussis vaccine was …

Importance The United States has experienced a nationwide resurgence of pertussis since
the mid-1970s, despite high estimated vaccine coverage. Short-lived immunity induced by …

OBJECTIVE: Data on the effectiveness of the diphtheria–tetanus–acellular pertussis (DTaP)
vaccine in the first 4 years of life are sparse. We evaluated the vaccine effectiveness (VE) of …

By 1947 the bacteria had already developed penicillin resistance. We are always behind in
the game we play with influenza virus every year, trying to pick the right strains for the …

The last 25 years have been tumultuous in re-gard to immunization for the prevention of
pertussis. 1 Although effective vaccines became available 50 years ago, exaggerated fears …

Abstract The Centers for Disease Control and Prevention's Advisory Committee on
Immunization Practices (ACIP), the American Academy of Pediatrics, and the American …