Epicardial versus endocardial closure: is one better than the other?

K Akella, B Yarlagadda, G Murtaza… - Cardiac …, 2020 - cardiacep.theclinics.com
Thrombus in the left atrial appendage (LAA) contributes to 90% of atrial fibrillation (AF)-
related strokes. 1 Whether it is the result of low flow state, the presence of scar tissue, or …

Left Atrial Appendage Closure: What the Evidence Does and Does Not Reveal—A View from the Outside

K Saraf, GM Morris - Cardiac Electrophysiology Clinics, 2023 - cardiacep.theclinics.com
It is well established that patients with atrial fibrillation (AF) have a significantly increased
risk of stroke and systemic embolism (SSE). Treatment with oral anticoagulation (OAC) …

[HTML][HTML] Left atrial appendage occlusion: what are the options and where is the evidence?

R Chava, MK Turagam… - The Journal of Innovations …, 2018 - ncbi.nlm.nih.gov
Left atrial appendage occlusion (LAAO) has emerged as an effective site-directed therapy in
patients with nonvalvular atrial fibrillation (AF) for stroke prevention, who are ineligible for …

Recent and upcoming randomized trials for left atrial appendage occlusion: Need for a definite assessment of the situation

C Skurk, JJ Hartung, U Landmesser - Herzschrittmachertherapie+ …, 2017 - Springer
Atrial fibrillation (AF) is the most common arrhythmia affecting more than 1.6 million patients
in Germany. Based on demographic developments, an the number is expected to increase …

[HTML][HTML] Left atrial appendage closure: when does a procedure become futile?

SJ Savona, EG Daoud - Clinical Electrophysiology, 2022 - jacc.org
Clinicians are often faced with a challenging clinical scenario regarding the management of
stroke risk in patients with atrial fibrillation (AF) who have elevated bleeding risk. When …

[HTML][HTML] Advances in left atrial appendage occlusion strategies

A Aryana, SM Singh, SK Doshi… - Journal of Atrial …, 2013 - ncbi.nlm.nih.gov
Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide and associated with
an elevated risk of thromboembolic stroke and systemic embolization. The evidence …

Left atrial appendage closure to prevent stroke in patients with atrial fibrillation: a call for the heart team approach

SP Salzberg, J Grünenfelder, MY Emmert - EP Europace, 2015 - academic.oup.com
With great interest we read the EHRA/EAPCI expert consensus statement on catheter-based
left atrial appendage (LAA) occlusion. 1 It is important to emphasize that the seminal efforts …

[HTML][HTML] Left atrial appendage closure for stroke prevention in AF: the quest for the Holy Grail

NAM Estes - Journal of the American College of Cardiology, 2015 - jacc.org
Strokes resulting from embolization of left atrial appendage (LAA) thrombi in patients with
atrial fibrillation (AF) account for up to 25% of the 700,000 cerebrovascular accidents …

Left atrial appendage closure: prevention and management of periprocedural and postprocedural complications

B Wilkins, M Fukutomi, O De Backer… - Cardiac …, 2020 - cardiacep.theclinics.com
An appropriately cautious uptake of left atrial appendage closure (LAAC) has followed from
early randomized trial evidence. In the PROTECT-AF 1 and PREVAIL 2 trials, LAAC was …

Left atrial appendage closure–indications, techniques, and outcomes: results of the European Heart Rhythm Association Survey

L Pison, TS Potpara, J Chen, TB Larsen… - EP …, 2015 - academic.oup.com
The purpose of this EP Wire was to assess the indications, techniques, and outcomes of left
atrial appendage occlusion (LAAO) in Europe. Thirty-three European centres, all members …