Alcohol as a modifiable risk factor for Alzheimer's disease—Evidence from experimental studies

DV Chandrashekar, RA Steinberg, D Han… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
cognitive impairment and memory loss. Epidemiological evidence suggests that heavy …

[HTML][HTML] Association between alcohol and Alzheimer's disease

WJ Huang, X Zhang, WW Chen - Experimental and …, 2016 - spandidos-publications.com
Alzheimer's disease (AD) is a neurodegenerative disease characterized by dense
deposition of amyloid-β (Aβ) protein in the brain, failure of the memory and dementia. At …

Role of alcohol drinking in Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis

B Peng, Q Yang, RB Joshi, Y Liu, M Akbar… - International journal of …, 2020 - mdpi.com
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD)
and amyotrophic lateral sclerosis (ALS), increase as the population ages around the world …

Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease

JL Hoffman, S Faccidomo, M Kim, SM Taylor… - International review of …, 2019 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that represents the
most common cause of dementia in the United States. Although the link between alcohol …

[HTML][HTML] Association of moderate alcohol intake with in vivo amyloid-beta deposition in human brain: A cross-sectional study

JW Kim, MS Byun, D Yi, JH Lee, K Ko, SY Jeon… - PLoS …, 2020 - journals.plos.org
Background An emerging body of literature has indicated that moderate alcohol intake may
be protective against Alzheimer disease (AD) dementia. However, little information is …

The association between alcohol use and the progression of Alzheimer's disease

D Heymann, Y Stern, S Cosentino… - Current Alzheimer …, 2016 - ingentaconnect.com
Objective: To examine the relationship between alcohol, both the amount and type, and
cognitive decline in a cohort of Alzheimer's disease (AD) patients. Methods: A cohort of 360 …

[HTML][HTML] Ethanol exposure alters Alzheimer's-related pathology, behavior, and metabolism in APP/PS1 mice

SM Day, SC Gironda, CW Clarke, JA Snipes… - Neurobiology of …, 2023 - Elsevier
Epidemiological studies identified alcohol use disorder (AUD) as a risk factor for Alzheimer's
disease (AD), yet there is conflicting evidence on how alcohol use promotes AD pathology …

Alcohol and Alzheimer's disease—does alcohol dependence contribute to beta-amyloid deposition, neuroinflammation and neurodegeneration in Alzheimer's disease …

A Venkataraman, N Kalk, G Sewell… - Alcohol and …, 2017 - academic.oup.com
Aims To investigate the underlying neurobiology between alcohol use, misuse and
dependence and cognitive impairment, particularly Alzheimer's disease (AD). Methods …

Are tobacco and alcohol use related to Alzheimer's disease? A critical assessment of the evidence and its implications

S Tyas - Addiction biology, 1996 - Wiley Online Library
Elucidation of the association of tobacco and alcohol use with Alzheimer's disease (AD) may
advance etiological hypotheses and provide a theoretical basis for treatment. There is …

A history of repeated alcohol intoxication promotes cognitive impairment and gene expression signatures of disease progression in the 3XTG mouse model of …

PP Sanna, C Cabrelle, T Kawamura, D Mercatelli… - Eneuro, 2023 - eneuro.org
The impact of alcohol abuse on Alzheimer's disease (AD) is poorly understood. Here, we
show that the onset of neurocognitive impairment in a mouse model of AD is hastened by …