TheEscherichia coliH-NS protein is one of the major constituents of the nucleoid structure.
This protein has been implicated not only in the compact organization of the nucleoid …

Despite many years of intense work investigating the function of nucleoid‐associated
proteins in prokaryotes, their role in bacterial physiology remains largely unknown. The two …

In Escherichia coli, pyrimidine-mediated regulation of upp expression occurs by UTP-
sensitive selection of alternative transcriptional start sites, which produces transcripts that …

Many bacterial promoters possess multiple sites for binding of transcriptional activator
proteins. The uhpT promoter, which controls expression of the sugar phosphate transport …

The Escherichia coli DNA‐binding protein H‐NS is known to interact specifically with the
upstream region of ribosomal RNA transcription units, where it causes transcriptional …

Extremely AT-rich DNA sequences present a challenging template for specific recognition by
RNA polymerase. In bacteria, this is because the promoter− 10 hexamer, the major DNA …

Transcriptional activation in prokaryotes can be mediated by at least two different
mechanisms: direct contacts between the activator and RNA polymerase or modulation of …

Highlights•Addresses the nature of the distinction between bacterial transcription factors and
nucleoid-associated proteins.•Proteins lie along a spectrum of influence extending from …

The genome DNA of Escherichia coli is associated with about 10 DNA-binding structural
proteins, altogether forming the nucleoid. The nucleoid proteins play some functional roles …

The proU operon of Escherichia coli encodes a high-affinity glycine betaine transport system
which is osmotically inducible and enables the organism to recover from the deleterious …