Neuroregulation of nonexercise activity thermogenesis and obesity resistance

CM Kotz, JA Teske… - American Journal of …, 2008 - journals.physiology.org
High levels of spontaneous physical activity in lean people and the nonexercise activity
thermogenesis (NEAT) derived from that activity appear to protect lean people from obesity …

Brain orexin promotes obesity resistance

C Kotz, J Nixon, T Butterick… - Annals of the New …, 2012 - Wiley Online Library
Resistance to obesity is becoming an exception rather than the norm, and understanding
mechanisms that lead some to remain lean in spite of an obesigenic environment is critical if …

Neuropeptidergic mediators of spontaneous physical activity and non-exercise activity thermogenesis

JA Teske, CJ Billington, CM Kotz - Neuroendocrinology, 2007 - karger.com
Lean individuals have high levels of spontaneous physical activity (SPA) and the energy
expenditure derived from that activity, termed non-exercise activity thermogenesis or NEAT …

Central neural and endocrine mechanisms of non‐exercise activity thermogenesis and their potential impact on obesity

CM Novak, JA Levine - Journal of neuroendocrinology, 2007 - Wiley Online Library
The rise in obesity is associated with a decline in the amount of physical activity in which
people engage. The energy expended through everyday non‐exercise activity, called non …

Physiological implications of orexins/hypocretins on energy metabolism and adipose tissue development

L Liu, Q Wang, A Liu, X Lan, Y Huang, Z Zhao, H Jie… - ACS …, 2019 - ACS Publications
Orexins/hypocretins and their receptors (OXRs) are ubiquitously distributed throughout the
nervous system and peripheral tissues. Recently, various reports have indicated that orexins …

Central orexin sensitivity, physical activity, and obesity in diet-induced obese and diet-resistant rats

CM Novak, CM Kotz, JA Levine - American Journal of …, 2006 - journals.physiology.org
Nonexercise activity thermogenesis (NEAT), the most variable component of energy
expenditure, can account for differential capacities for human weight gain. Also highly …

Nonexercise activity thermogenesis (NEAT): environment and biology

JA Levine - American Journal of Physiology-Endocrinology …, 2004 - journals.physiology.org
Nonexercise activity thermogenesis (NEAT) is the energy expended for everything that is not
sleeping, eating, or sports-like exercise. It includes the energy expended walking to work …

Orexin activation counteracts decreases in nonexercise activity thermogenesis (NEAT) caused by high-fat diet

PE Bunney, AN Zink, AA Holm, CJ Billington… - Physiology & …, 2017 - Elsevier
Overweight and obesity result from an imbalance between caloric intake and energy
expenditure, including expenditure from spontaneous physical activity (SPA). Changes in …

Integration of feeding and spontaneous physical activity: role for orexin

CM Kotz - Physiology & behavior, 2006 - Elsevier
Spontaneous physical activity is activity that is non-volitional, or subconscious, such as
fidgeting and shifting in one's seat, and time spent moving (standing and ambulating) …

Orexin: pathways to obesity resistance?

TA Butterick, CJ Billington, CM Kotz… - Reviews in Endocrine and …, 2013 - Springer
Obesity has increased in prevalence worldwide, attributed in part to the influences of an
obesity-promoting environment and genetic factors. While obesity and overweight …