Integrative brain network and salience models of psychopathology and cognitive dysfunction in schizophrenia
Brain network models of cognitive control are central to advancing our understanding of
psychopathology and cognitive dysfunction in schizophrenia. This review examines the role …
psychopathology and cognitive dysfunction in schizophrenia. This review examines the role …
Dysregulated brain dynamics in a triple-network saliency model of schizophrenia and its relation to psychosis
Background Schizophrenia is a highly disabling psychiatric disorder characterized by a
range of positive “psychosis” symptoms. However, the neurobiology of psychosis and …
range of positive “psychosis” symptoms. However, the neurobiology of psychosis and …
The concept of salience network dysfunction in schizophrenia: from neuroimaging observations to therapeutic opportunities
L Palaniyappan, TP White… - Current topics in medicinal …, 2012 - ingentaconnect.com
A large body of neuroimaging literature suggests that distributed regions in the brain form
coordinated largescale networks that show reliable patterns of connectivity when observed …
coordinated largescale networks that show reliable patterns of connectivity when observed …
[HTML][HTML] Glutamate and dysconnection in the salience network: neurochemical, effective connectivity, and computational evidence in schizophrenia
Background Functional dysconnection in schizophrenia is underwritten by a
pathophysiology of the glutamate neurotransmission that affects the excitation-inhibition …
pathophysiology of the glutamate neurotransmission that affects the excitation-inhibition …
[HTML][HTML] Neural primacy of the salience processing system in schizophrenia
For effective information processing, two large-scale distributed neural networks appear to
be critical: a multimodal executive system anchored on the dorsolateral prefrontal cortex …
be critical: a multimodal executive system anchored on the dorsolateral prefrontal cortex …
Abnormal salience signaling in schizophrenia: The role of integrative beta oscillations
Aberrant salience attribution and cerebral dysconnectivity both have strong evidential
support as core dysfunctions in schizophrenia. Aberrant salience arising from an excess of …
support as core dysfunctions in schizophrenia. Aberrant salience arising from an excess of …
Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia
Theories of schizophrenia propose that abnormal functioning of the neural reward system is
linked to negative and psychotic symptoms, by disruption of reward processing and …
linked to negative and psychotic symptoms, by disruption of reward processing and …
Links among resting-state default-mode network, salience network, and symptomatology in schizophrenia
Neuroimaging data support the idea that schizophrenia is a brain disorder with altered brain
structure and function. New resting-state functional connectivity techniques allow us to …
structure and function. New resting-state functional connectivity techniques allow us to …
[HTML][HTML] Effective connectivity of the right anterior insula in schizophrenia: the salience network and task-negative to task-positive transition
Triple network dysfunction theory of schizophrenia postulates that the interaction between
the default-mode and the fronto-parietal executive network is disrupted by aberrant salience …
the default-mode and the fronto-parietal executive network is disrupted by aberrant salience …
[HTML][HTML] Dysregulated but not decreased salience network activity in schizophrenia
Effective estimation of the salience of environmental stimuli underlies adaptive behavior,
while related aberrance is believed to undermine rational thought processes in …
while related aberrance is believed to undermine rational thought processes in …
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