[HTML][HTML] Anti-Alzheimer Activity of Combinations of Cocoa with Vinpocetine or Other Nutraceuticals in Rat Model: Modulation of Wnt3/β-Catenin/GSK-3β/Nrf2/HO-1 and …

K Abu-Elfotuh, AMA Tolba, FH Hussein, AME Hamdan… - Pharmaceutics, 2023 - mdpi.com
Alzheimer's disease (AD) is a devastating illness with limited therapeutic interventions. The
aim of this study is to investigate the pathophysiological mechanisms underlying AD and …

[HTML][HTML] Flavonoids as prospective neuroprotectants and their therapeutic propensity in aging associated neurological disorders

M Ayaz, A Sadiq, M Junaid, F Ullah, M Ovais… - Frontiers in aging …, 2019 - frontiersin.org
Modern research has revealed that dietary consumption of flavonoids and flavonoids-rich
foods significantly improve cognitive capabilities, inhibit or delay the senescence process …

[HTML][HTML] Characterization of orange peel extract and its potential protective effect against aluminum chloride-induced Alzheimer's disease

NM Abd El-Aziz, MG Shehata, T Alsulami, AN Badr… - Pharmaceuticals, 2022 - mdpi.com
Alzheimer's disease (AD) is a devastating neurodegenerative disorder without a cure.
Hence, developing an effective treatment or protective agent is crucial for public health. The …

[HTML][HTML] Neuroprotective effects of phytochemicals against aluminum chloride-induced Alzheimer's disease through ApoE4/LRP1, wnt3/β-catenin/gsk3β, and TLR4 …

AME Hamdan, FHJ Alharthi, AH Alanazi, SZ El-Emam… - Pharmaceuticals, 2022 - mdpi.com
Background: Alzheimer's disease (AD) is a neurodegenerative disorder that is associated
with abnormal cognition. AD is aided in its initiation and progression by hereditary and …

The influence of vinpocetine alone or in combination with Epigallocatechin-3-gallate, Coenzyme COQ10, Vitamin E and Selenium as a potential neuroprotective …

AA Ali, MG Khalil, DM Abd El-Latif, T Okda… - Archives of Gerontology …, 2022 - Elsevier
Alzheimer's disease (AD) is one of such diseases that represent the most prominent cause
of dementia in elderly people. To explore the possible neuroprotective effect as well as …

[HTML][HTML] Possible prophylactic anti-excitotoxic and anti-oxidant effects of virgin coconut oil on aluminium chloride-induced Alzheimer's in rat models

BSA Alghamdi - Journal of integrative neuroscience, 2018 - content.iospress.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease that affects an
estimated 5.4 million people worldwide. However, there remains no curative treatment for …

[HTML][HTML] Caffeic acid phenethyl ester (CAPE) prevents development of STZ-ICV induced dementia in rats

M Kumar, D Kaur, N Bansal - Pharmacognosy Magazine, 2017 - ncbi.nlm.nih.gov
Background: Chronic oxidative stress and inflammation severely affect the normal
physiology of neurons and lead to neurodegenerative disorders such as Alzheimer's …

[HTML][HTML] Multitarget effects of coconut oil (virgin type) on Aβ-induced Alzheimer's disease animal model

F Mirzaei, M Khazaei, A Komaki, I Amiri… - Archives of …, 2019 - brieflands.com
Background: Almost 5% of people over 65 and 35% of those over 80 years of age have
Alzheimer's disease (AD). Objectives: The current study evaluated the neuroprotective …

[PDF][PDF] Comparative study on the influence of epigallocatechin-3-gallate and/or coenzyme Q10 against Alzheimer's disease induced by aluminium in normally-fed and …

AA Ali, HI Ahmed, MG Khalil, AI Alwakeel… - J Alzheimers Dis …, 2016 - researchgate.net
Background: Alzheimer's disease (AD) is a neurodegenerative disorder greatly influenced
by oxidative stress and mitochondrial dysfunction which may lead to deposition of β-amyloid …

Neuroprotective effect of quercetin through targeting key genes involved in aluminum chloride induced Alzheimer's disease in rats

HA Elreedy, AM Elfiky, AA Mahmoud… - Egyptian Journal of …, 2023 - Taylor & Francis
Alzheimer's disease (AD) is a neurodegenerative disorder that is clinically characterized by
deteriorating cognitive function. Quercetin (Q), a bioflavonoid, has been reported to slow …