VacA and CagA Status as Biomarker of Two Opposite End Outcomes of Helicobacter pylori Infection (Gastric Cancer and Duodenal Ulcer) in a Moroccan Population

M El Khadir, S Alaoui Boukhris, DA Benajah… - PloS one, 2017 - journals.plos.org
Helicobacter pylori (H. pylori) infection induces inflammation of the gastric mucosa, which
may progress to precancerous lesions leading to gastric cancer. Pathological determinism is …

Clinical and pathological importance of vacA allele heterogeneity and cagA status in peptic ulcer disease in patients from North Brazil

LC Martins, TCO Corvelo, S Demachki… - Memórias do Instituto …, 2005 - SciELO Brasil
We have examined the prevalence of gene cagA and vacA alleles in 129 patients, 69 with
gastritis and 60 with peptic ulcer diseases from North Brazil and their relation with …

[HTML][HTML] Diversity of Helicobacter pylori cagA and vacA genes and its relationship with clinical outcomes in Azerbaijan, Iran

R Ghotaslou, M Milani, MT Akhi… - Advanced …, 2013 - ncbi.nlm.nih.gov
Purpose: The purpose of this research was to analyze cagA and vacA genotypes status in H.
pylori isolates and relationship with clinical outcomes. Methods: Gastric biopsy specimens …

Genotypying of clinical isolates of Helicobacter pylori by cagA, vacA and babA2 virulence associated genes. First detection of a babA2 positive strain in Chilean …

A García, R Barra, C Delgado, F Kawaguchi… - Revista medica de …, 2006 - europepmc.org
Background Helicobacter pylori-associated gastroduodenal diseases depends on host
characteristics, environmental conditions and bacterial virulence factors, such as cagA, vacA …

Genotyping of Helicobacter pylori strains isolated from patients with gastric ulcer and non ulcer disease using RFLP-PCR of ureAB, vacA, cagA genes

S Farshad, A Japoni, A Alborzi… - Avicenna Journal of …, 2008 - sjh.umsha.ac.ir
Results: The prevalence of vacA-positive strains in ulcerative patients was significantly more
than that in non ulcerative patients (P< 0.05). RFLP analysis revealed two different patterns …

Helicobacter pylori genotypes may determine gastric histopathology

C Nogueira, C Figueiredo, F Carneiro… - The American journal of …, 2001 - Elsevier
The outcome of Helicobacter pylori infection has been associated with specific virulence-
associated bacterial genotypes. The present study aimed to investigate the gastric …

Investigation of the association between clinical outcome and the cag pathogenicity-island and other virulence genes of Helicobacter pylori isolates from patients with …

G Ozbey, U Demirel, C Aygun, HB Ertas - Brazilian Journal of …, 2013 - SciELO Brasil
The aims of our work were to determine the presence of the cag pathogenicity-island (cag
PAI) and other virulence genes of Helicobacter pylori recovered from patients with gastritis …

Genetic characterization of Helicobacter pylori vacA and cagA genes in Thai gastro-duodenal and hepatobiliary patients

W Boonyanugomol, N Khuntikeo, A Pugkhem… - The Journal of Infection …, 2017 - jidc.org
Introduction: H. pylori has been detected in patients with hepatobiliary diseases. It is
currently unclear whether the H. pylori detected in hepatobiliary patients are genetically …

Prevalence of Helicobacter pylori vacA, cagA, and iceA Genotypes in Cuban Patients with Upper Gastrointestinal Diseases

O Feliciano, O Gutierrez, L Valdés… - BioMed research …, 2015 - Wiley Online Library
Virulence factors of Helicobacter pylori can predict the development of different
gastroduodenal diseases. There are scarce reports in Cuba about H. pylori isolates …

CagA and vacA allelic combination of Helicobacter pylori in gastroduodenal disorders

AF Sheikh, MJ Yadyad, H Goodarzi, SJ Hashemi… - Microbial …, 2018 - Elsevier
Background Allelic variation of the virulence genes, vacA and cagA, as the most important
virulence associated genes play an important role in the pathogenesis of severe …