Diverse roles of RNA‐binding proteins in cancer traits and their implications in gastrointestinal cancers

K Masuda, Y Kuwano - Wiley Interdisciplinary Reviews: RNA, 2019 - Wiley Online Library
Gene expression patterns in cancer cells are strongly influenced by posttranscriptional
mechanisms. RNA‐binding proteins (RBPs) play key roles in posttranscriptional gene …

RNA-binding proteins in cancer: old players and new actors

B Pereira, M Billaud, R Almeida - Trends in cancer, 2017 - cell.com
RNA-binding proteins (RBPs) are key players in post-transcriptional events. The
combination of versatility of their RNA-binding domains with structural flexibility enables …

Versatility of RNA‐binding proteins in cancer

L Wurth - International Journal of Genomics, 2012 - Wiley Online Library
Posttranscriptional gene regulation is a rapid and efficient process to adjust the proteome of
a cell to a changing environment. RNA‐binding proteins (RBPs) are the master regulators of …

[HTML][HTML] RNA-binding proteins in cancer: functional and therapeutic perspectives

D Kang, Y Lee, JS Lee - Cancers, 2020 - mdpi.com
Simple Summary RNA-binding proteins (RBPs) play central roles in regulating
posttranscriptional expression of genes. Many of them are known to be deregulated in a …

[PDF][PDF] Comprehensive genomic characterization of RNA-binding proteins across human cancers

ZL Wang, B Li, YX Luo, Q Lin, SR Liu, XQ Zhang… - Cell reports, 2018 - cell.com
RNA-binding proteins (RBPs) regulate the expression of thousands of transcripts, and some
are reported to be involved in human tumorigenesis. However, little is known about the …

[HTML][HTML] Post-transcriptional regulation of colorectal cancer: a focus on RNA-binding proteins

JM García-Cárdenas, S Guerrero… - Frontiers in molecular …, 2019 - frontiersin.org
Colorectal cancer (CRC) is a major health problem with an estimated 1. 8 million new cases
worldwide. To date, most CRC studies have focused on DNA-related aberrations, leaving …

The oncogenic and tumor suppressive roles of RNA‐binding proteins in human cancers

A Bitaraf, E Razmara, B Bakhshinejad… - Journal of cellular …, 2021 - Wiley Online Library
Posttranscriptional regulation is a mechanism for the cells to control gene regulation at the
RNA level. In this process, RNA‐binding proteins (RBPs) play central roles and orchestrate …

A comprehensive expression landscape of RNA-binding proteins (RBPs) across 16 human cancer types

B Zhang, KR Babu, CY Lim, ZH Kwok, J Li, S Zhou… - RNA biology, 2020 - Taylor & Francis
ABSTRACT RNA-binding proteins (RBPs) are key regulators of posttranscriptional
processes such as RNA maturation, localization, turnover and translation. Despite their …

RNA-binding proteins: Underestimated contributors in tumorigenesis

Y Zhao, C Mir, Y Garcia-Mayea, R Paciucci… - Seminars in Cancer …, 2022 - Elsevier
Abstract mRNA export, translation, splicing, cleavage or capping determine mRNA stability,
which represents one of the primary aspects regulating gene expression and function. RNA …

Cancer the 'RBP'eutics–RNA-binding proteins as therapeutic targets for cancer

S Mohibi, X Chen, J Zhang - Pharmacology & therapeutics, 2019 - Elsevier
RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …