[HTML][HTML] Mitochondrial-targeted antioxidant maintains blood flow, mitochondrial function, and redox balance in old mice following prolonged limb ischemia
S Miura, S Saitoh, T Kokubun, T Owada… - International Journal of …, 2017 - mdpi.com
Aging is a major factor in the decline of limb blood flow with ischemia. However, the
underlying mechanism remains unclear. We investigated the role of mitochondrial reactive …
underlying mechanism remains unclear. We investigated the role of mitochondrial reactive …
Mitochondria‐specific antioxidant supplementation does not influence endurance exercise training‐induced adaptations in circulating angiogenic cells, skeletal …
DD Shill, WM Southern, TB Willingham… - The Journal of …, 2016 - Wiley Online Library
Key points Reducing excessive oxidative stress, through chronic exercise or antioxidants,
can decrease the negative effects induced by excessive amounts of oxidative stress …
can decrease the negative effects induced by excessive amounts of oxidative stress …
Acute mitochondrial antioxidant intake improves endothelial function, antioxidant enzyme activity, and exercise tolerance in patients with peripheral artery disease
Peripheral artery disease (PAD) is a manifestation of atherosclerosis in the leg arteries,
which causes claudication. This may be in part due to vascular mitochondrial dysfunction …
which causes claudication. This may be in part due to vascular mitochondrial dysfunction …
Chronic mitochondria antioxidant treatment in older adults alters the circulating milieu to improve endothelial cell function and mitochondrial oxidative stress
Excessive reactive oxygen species production by mitochondria (mtROS) is a key contributor
to age-related vascular endothelial dysfunction. We recently showed in a crossover design …
to age-related vascular endothelial dysfunction. We recently showed in a crossover design …
Exercise training improves vascular mitochondrial function
SY Park, MJ Rossman, JR Gifford… - American Journal …, 2016 - journals.physiology.org
Exercise training is recognized to improve cardiac and skeletal muscle mitochondrial
respiratory capacity; however, the impact of chronic exercise on vascular mitochondrial …
respiratory capacity; however, the impact of chronic exercise on vascular mitochondrial …
Aging exacerbates pressure-induced mitochondrial oxidative stress in mouse cerebral arteries
Epidemiological studies demonstrate that in addition to the increased prevalence of
hypertension in old patients, the deleterious cerebrovascular effects of hypertension …
hypertension in old patients, the deleterious cerebrovascular effects of hypertension …
Habitual exercise and vascular ageing
Age is the major risk factor for cardiovascular diseases (CVD) and this is attributable in part
to stiffening of large elastic arteries and development of vascular endothelial dysfunction (eg …
to stiffening of large elastic arteries and development of vascular endothelial dysfunction (eg …
Short‐term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress
To determine if short‐term calorie restriction reverses vascular endothelial dysfunction in old
mice, old (O, n= 30) and young (Y, n= 10) male B6D2F1 mice were fed ad libitum (AL) or …
mice, old (O, n= 30) and young (Y, n= 10) male B6D2F1 mice were fed ad libitum (AL) or …
[HTML][HTML] Regular exercise delays microvascular endothelial dysfunction by regulating antioxidant capacity and cellular metabolism
G Scarfò, S Daniele, E Chelucci, A Rizza, J Fusi… - Scientific Reports, 2023 - nature.com
Aging is the basis for several unfavorable conditions, including cardiovascular diseases
(CVDs). In this sense, regular physical activity (regular PA) has been proven to delay cellular …
(CVDs). In this sense, regular physical activity (regular PA) has been proven to delay cellular …
Age-associated mitochondrial dysfunction accelerates atherogenesis
Rationale: Aging is one of the strongest risk factors for atherosclerosis. Yet whether aging
increases the risk of atherosclerosis independently of chronic hyperlipidemia is not known …
increases the risk of atherosclerosis independently of chronic hyperlipidemia is not known …