Previous studies have shown that the aging vascular system undergoes pro-atherogenic
phenotypic changes, including increased oxidative stress and a pro-inflammatory shift in …

Aging is characterized by increased aortic stiffness, an early, independent predictor and
cause of cardiovascular disease. Oxidative stress from excess reactive oxygen species …

Healthy brain aging and cognitive function are promoted by exercise. The benefits of
exercise are attributed to several mechanisms, many which highlight its neuroprotective role …

Human aging is accompanied by both vascular and cognitive changes. Although arteries
throughout the body are known to become stiffer with age, this vessel hardening is believed …

Exercise is good for you. Elite athletes live longer than the general population (Teramoto &
Bungum, 2009). Physically active middle-aged men live on average 2.3 years longer than …

Mitochondrial redox metabolism has long been recognized as being central to the effects of
aging and the development of age-related pathologies in the major oxidative organs …

Systemic and central cardiovascular adaptations may vary in response to chronic exercise
performed with different intensities and volumes. This study compared the effects of aerobic …

Sarcopenia is a common skeletal muscle degenerative disease characterized by decreased
skeletal muscle mass and mitochondrial dysfunction that involves microRNAs (miR) as …

Aging is a major risk factor for cognitive impairment. Aerobic exercise benefits brain function
and may promote cognitive health in older adults. However, underlying biological …

Hormesis plays a critical role in producing some major benefits derived from physical
exercise. However whether these known cellular mechanisms are applicable to ameliorate …