Continuous estimates of dynamic cerebral autoregulation during transient hypocapnia and hypercapnia

NE Dineen, FG Brodie, TG Robinson… - Journal of applied …, 2010 - journals.physiology.org
Dynamic cerebral autoregulation (CA) is the transient response of cerebral blood flow (CBF)
to rapid blood pressure changes: it improves in hypocapnia and becomes impaired during …

Hypertension and cerebrovascular dysfunction

C Iadecola, RL Davisson - Cell metabolism, 2008 - cell.com
Essential hypertension has devastating effects on the brain, being the major cause of stroke
and a leading cause of dementia. Hypertension alters the structure of cerebral blood vessels …

The effects of hypertension on the cerebral circulation

PW Pires, CM Dams Ramos, N Matin… - American Journal of …, 2013 - journals.physiology.org
Maintenance of brain function depends on a constant blood supply. Deficits in cerebral
blood flow are linked to cognitive decline, and they have detrimental effects on the outcome …

The lower limit of cerebral blood flow autoregulation is increased with elevated intracranial pressure

KM Brady, JK Lee, KK Kibler, RB Easley… - Anesthesia & …, 2009 - journals.lww.com
BACKGROUND: The cerebral perfusion pressure that denotes the lower limit of cerebral
blood flow autoregulation (LLA) is generally considered to be equivalent for reductions in …

Grading of cerebral dynamic autoregulation from spontaneous fluctuations in arterial blood pressure

RB Panerai, RP White, HS Markus, DH Evans - Stroke, 1998 - Am Heart Assoc
Background and Purpose—Assessment of cerebral autoregulation has been traditionally
performed with static changes in arterial blood pressure. Newer dynamic methods require …

Blood pressure and the brain: how low can you go?

JC Drummond - Anesthesia & Analgesia, 2019 - journals.lww.com
There are occasionally intraoperative circumstances in which reduction of mean arterial
pressure (MAP) to levels well below those that occur in nonanesthetized adults is necessary …

Neurovascular regulation in the ischemic brain

K Jackman, C Iadecola - Antioxidants & redox signaling, 2015 - liebertpub.com
Significance: The brain has high energetic requirements and is therefore highly dependent
on adequate cerebral blood supply. To compensate for dangerous fluctuations in cerebral …

Dynamic cerebral autoregulation is transiently impaired for one week after large-vessel acute ischemic stroke

NH Petersen, S Ortega-Gutierrez, A Reccius… - Cerebrovascular …, 2015 - karger.com
Background: Dynamic cerebral autoregulation (DCA) is the continuous counterregulation of
cerebral blood flow to fluctuations in blood pressure. DCA can become impaired after acute …

Assessment of cerebrovascular and cardiovascular responses to lower body negative pressure as a test of cerebral autoregulation

CM Brown, M Dütsch, MJ Hecht, B Neundörfer… - Journal of the …, 2003 - Elsevier
The aim of this study was to determine whether lower body negative pressure (LBNP),
combined with noninvasive methods of assessing changes in systemic and cerebral …

A lumped parameter model of cerebral blood flow control combining cerebral autoregulation and neurovascular coupling

B Spronck, EGHJ Martens… - American Journal …, 2012 - journals.physiology.org
Cerebral blood flow regulation is based on a variety of different mechanisms, of which the
relative regulatory role remains largely unknown. The cerebral regulatory system expresses …