Neurotrophic factors are important regulators of the development and maintenance of
vertebrate nervous systems (reviewed in Korsching, 1993; Eide et al., 1993); Farinas and …

The Neurotrophic Hypothesis Programmed neuronal cell death is a prominent feature of
vertebrate embryonic development. Timing and extent of cell death are dependent on the …

The development and maintenance of the vertebrate nervous system depends on neuronal
survival proteins known as neurotrophic factors (for review, see Snider and Johnson 1989) …

The neurotrophic factor concept in its basic form envisages that innervated tissues produce
a signal for the innervating neurons for the selective limitation of neuronal death occurring …

824 RAFFIONI ET AL brane, and internal domains. The primary functional purpose of the
external domain is recognition, while that of the internal domain is signal transmission. The …

In the manner of many other growth factors, the prototypical neurotrophic factor, nerve
growth factor (NGF), has recently been found to be a member of a small gene family …

The gene family of neurotrophins includes nerve growth factor (NGF), brain‐derived
neurotrophic factor (BDNF), neurotrophin‐3 (NT‐3), and neurotrophin‐4 (NT‐4). Recently …

Nerve growth factor (NGF) has long occupied a central position in developmental
neurobiology because of the many important neuronal functions it has been shown to …

Neurotrophic Factors: Neurotrophin autocrine loops: Current Biology Skip to Main Content
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Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin-3
(NT-3) are small, basic, secretory proteins that allow the survival of specific neuronal …