[PDF][PDF] Stevens-Johnson syndrome and toxic epidermal necrolysis: clinical patterns, diagnostic considerations, etiology, and therapeutic management

M Mockenhaupt - Semin Cutan Med Surg, 2014 - academia.edu
They include Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), but
also acute generalized exanthematous pustulosis (AGEP) and drug-induced hypersensitivity …

Severe cutaneous adverse reactions: acute generalized exanthematous pustulosis, toxic epidermal necrolysis and Stevens-Johnson syndrome

T Harr, LE French - Medical Clinics, 2010 - medical.theclinics.com
Most drug hypersensitivity reactions show skin symptoms. The most severe cutaneous
manifestations include pustular and bullous skin eruptions. These 2 manifestations can lead …

Severe cutaneous adverse drug reactions: a clinicoepidemiological study

S Sasidharanpillai, N Riyaz, A Khader… - Indian journal of …, 2015 - journals.lww.com
Background: Drug eruptions range from transient erythema to the life threatening severe
cutaneous adverse reactions (SCAR) that encompass Stevens–Johnson syndrome (SJS) …

Recent advances in the genetics and immunology of Stevens-Johnson syndrome and toxic epidermal necrosis

WH Chung, SI Hung - Journal of dermatological science, 2012 - Elsevier
Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) are rare but life-
threatening severe cutaneous adverse reactions (SCARs), which are majorly (65–75%) …

Life-threatening acute adverse cutaneous drug reactions

R Wolf, E Orion, B Marcos, H Matz - Clinics in dermatology, 2005 - Elsevier
Adverse cutaneous reactions to drugs are frequent, affecting 2% to 3% of all hospitalized
patients. Fortunately, only about 2% of adverse cutaneous reactions are severe and very few …

Severe drug‐induced skin reactions: clinical pattern, diagnostics and therapy

M Mockenhaupt - JDDG: Journal der Deutschen …, 2009 - Wiley Online Library
The spectrum of severe drug‐induced skin reactions includes not only Stevens‐Johnson
syndrome (SJS) and toxic epidermal necrolysis (TEN) but also generalized bullous fixed …

Sequelae in 145 patients with drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms: survey conducted by the Asian …

Y Kano, M Tohyama, M Aihara… - The Journal of …, 2015 - Wiley Online Library
Drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic
symptoms (DIHS/DRESS) is a severe adverse drug reaction caused by specific drug. It is …

[HTML][HTML] Drug reaction with eosinophilia and systemic symptoms: a drug-induced hypersensitivity syndrome with variable clinical features

YC Chen, YT Cho, CY Chang, CY Chu - Dermatologica sinica, 2013 - Elsevier
Drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced
hypersensitivity syndrome (DIHS) involves a unique and severe adverse drug reaction …

Defective regulatory T cells in patients with severe drug eruptions: timing of the dysfunction is associated with the pathological phenotype and outcome

R Takahashi, Y Kano, Y Yamazaki… - The Journal of …, 2009 - journals.aai.org
Toxic epidermal necrolysis (TEN) and drug-induced hypersensitivity syndrome (DIHS)
represent two ends of a spectrum of severe drug eruptions: DIHS is unique in that severe …

Making a diagnosis in severe cutaneous drug hypersensitivity reactions

MR Ardern-Jones, M Mockenhaupt - Current Opinion in Allergy …, 2019 - journals.lww.com
Careful phenotypic analysis of the increasingly complex recognized patterns of SCAR
facilitates the enhancement in our understanding of T-cell mediated drug hypersensitivity …