Self-propelled and near-infrared-phototaxic photosynthetic bacteria as photothermal agents for hypoxia-targeted cancer therapy

P Zheng, M Fan, H Liu, Y Zhang, X Dai, H Li, X Zhou… - ACS …, 2020 - ACS Publications
Hypoxia can increase the resistance of tumor cells to radiotherapy and chemotherapy.
However, the dense extracellular matrix, high interstitial fluid pressure, and irregular blood …

Antivascular Treatment of Solid Melanoma Tumors with Bacteriochlorophyll–serine‐based Photodynamic Therapy¶

J Zilberstein, S Schreiber… - Photochemistry and …, 2001 - Wiley Online Library
We describe here a strategy for photodynamic eradication of solid melanoma tumors that is
based on photoinduced vascular destruction. The suggested protocol relies on …

In-situ synthesis of melanin in tumor with engineered probiotics for hyperbaric oxygen-synergized photothermal immunotherapy

Y Xiao, D Wang, B Luo, X Chen, Y Yao, C Song, M Wu… - Nano Today, 2022 - Elsevier
Anaerobic bacteria and facultative anaerobe are usually used as delivery carriers of
antitumor drugs because of their tumor hypoxia targeting and antitumor immune activation …

Combination of bacterial‐photothermal therapy with an anti‐PD‐1 peptide depot for enhanced immunity against advanced cancer

W Chen, Z Guo, Y Zhu, N Qiao… - Advanced functional …, 2020 - Wiley Online Library
Photothermal therapy (PTT) is a promising cancer treatment, but it has so far proven
successful only with relatively small subcutaneous tumors in animal models. Treating larger …

Cell membrane-based biomimetic technology for cancer phototherapy: mechanisms, recent advances and perspectives

S Li, X Meng, B Peng, J Huang, J Liu, H Xiao, L Ma… - Acta biomaterialia, 2023 - Elsevier
Despite significant advances in medical technology and antitumour treatments, the
diagnosis and treatment of tumours have undergone remarkable transformations …

Genetically modified bacteria for targeted phototherapy of tumor

X Deng, W Yang, Z Shao, Y Zhao - Biomaterials, 2021 - Elsevier
Live attenuated bacteria have been used as target vehicles for genetic therapy of malignant
carcinoma because they can be reprogrammed by following simple genetic rules and have …

Smart polymeric delivery system for antitumor and antimicrobial photodynamic therapy

Z Wang, FJ Xu, B Yu - Frontiers in Bioengineering and Biotechnology, 2021 - frontiersin.org
Photodynamic therapy (PDT) has attracted tremendous attention in the antitumor and
antimicrobial areas. To enhance the water solubility of photosensitizers and facilitate their …

Spatiotemporally controllable distribution of combination therapeutics in solid tumors by dually modified bacteria

L Wang, Z Cao, M Zhang, S Lin, J Liu - Advanced Materials, 2022 - Wiley Online Library
Methods capable of distributing antitumor therapeutics uniformly and durably throughout an
entire tumor would be of great significance in maximizing their treatment efficacy, but they …

Targeted photodynamic therapy of established soft-tissue infections in mice

F Gad, T Zahra, KP Francis, T Hasan… - Photochemical & …, 2004 - pubs.rsc.org
The worldwide rise in antibiotic resistance necessitates the development of novel
antimicrobial strategies. Although many workers have used photodynamic therapy (PDT) to …

From plasma membrane to mitochondria: Time-dependent photodynamic antibacterial and anticancer therapy with a near-infrared AIE-active photosensitizer

MY Wu, ZJ Wu, Q Zou, JL Wang, C Kam, S Chen… - Chemical Engineering …, 2023 - Elsevier
Multi-functional photosensitizers (PSs) with time-dependent subcellular localizations for
defined and multiple targets are highly desirable for smart therapy but rarely reported …