Synthesis, quantum mechanical studies, physicochemical properties and molecular docking studies of Schiff base NN-(1, 2-Phenylene) Bis (1-(4-Bromophenyl) …

TS Ganesan, N Elangovan, A Sirajunnisa… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Schiff bases have advanced physical, chemical, and medicinal properties, making them
strong biological agents. Comparable FTIR, UV-VIS, 1HNMR, 13CNMR spectra confirmed …

Synthesis, Single Crystal X-Ray, Hirshfeld Surface Analysis and DFT Calculation Based NBO, HOMO–LUMO, MEP, ECT and Molecular Docking Analysis of N′-[(2,6 …

A Suhta, S Saral, U Çoruh, S Karakuş… - Journal of Structural …, 2024 - Springer
A new Schiff base compound of N′-[(2, 6-dichlorophenyl) methylidene]-2-{[3-(trifluoro-
methyl) phenyl] amino} benzohydrazide was synthesized and characterized through various …

Design, syntheses, theoretical calculations, MM-GBSA, potential anti-cancer and enzyme activities of novel Schiff base compounds

H Yalazan, D Koç, F Aydın Kose… - Journal of …, 2023 - Taylor & Francis
In this study, new Schiff base compounds (SB-F-OH, SB-Cl-OH and SB-Br-OH) were derived
from chalcone-derived amine compounds containing halogen groups and 4 …

[PDF][PDF] Synthesis, characterisation, an d biological and computational studies of novel schiff bases from heterocycli c molecules

SA Aghaward, LJ Abbas, KA Hussein - J. Med. Chem. Sci., 2023 - faculty.uobasrah.edu.iq
The products obtained from the condensation of carbonyl and the primary amine
compounds are called Schiff bases, named after Hugo Schiff, who recorded the first …

Molecular docking of some novel quinoline derivatives as potent inhibitors of human breast cancer cell line

MO Idris, SE Adeniji, K Habib, AA Adeiza - Lab-in-Silico, 2021 - sciengpub.ir
Breast Cancer is one of the major universal health problems affecting more than one million
cases per year. Incidence of breast cancer would be seriously increased by inefficacy of the …

Syntheses, molecular docking study and anticancer activity examination of p-methoxycinnamoyl hydrazides

MI Sulistyowati, J Ekowati… - International Journal of …, 2016 - repository.unair.ac.id
In this study, we attempted to develop a potential anticancer drug by synthesizing some of p-
methoxycinnamoyl hidrazides. The compounds were synthesized from the ethyl p …

Synthesis, spectral characterization, chemical reactivity and anticancer behaviors of some novel hydrazone derivatives: Experimental and theoretical insights

R Çakmak, E Başaran, S Kaya, S Erkan - Journal of Molecular Structure, 2022 - Elsevier
In this research, two new hydrazone derivatives; namely compound 1 (N'-(4-((2-
hydroxyethyl)(methyl) amino) benzylidene) nicotinohydrazide) and compound 2 (N'-(4-((2 …

[HTML][HTML] Molecular docking and in vitro biological studies of a Schiff base ligand as anticancer and antibacterial agents

P Babaei, VH Rezvan, NS Gilani, SR Mansour - Results in Chemistry, 2024 - Elsevier
In this study, a bis-Schiff base ligand of N, N'-bis (4-dimethylaminobenzylidene) hexane-1, 6-
diamine (L) was obtained via a condensation reaction of N, N-dimethylaminobenzaldehyde …

Designed, Synthesis, In Vitro and Computational Analyses of Anticancer Nicotinamide Derivatives

M GÖMEÇ, V NASİF, AHT KAFA, K SAYIN… - Indian Journal of …, 2024 - or.niscpr.res.in
The search for ideal treatment continues for many health problems such as cancer and
infection. In this context, new synthesis compounds have been promising and the …

Synthesis, structure analysis, biological activity and molecular docking studies of some hydrazones derived from 4-aminobenzohydrazide

S Senthilkumar, J Seralathan… - Journal of Molecular …, 2021 - Elsevier
Abstract (E)-4-Amino-N′-(substituted benzylidene) benzohydrazides (1-8) were
synthesized by condensing 4-aminobenzohydrazide with an appropriate aldehyde in the …