We synthesized a novel series of (E)-2-((substituted phenyl) diazenyl) phenyl 4-
methylbenzenesulfonate derivatives (2 and 3) and (E)-2-((substituted phenyl) diazenyl) …

Ten azo compounds including azo-resveratrol (5) and azo-oxyresveratrol (9) were
synthesized using a modified Curtius rearrangement and diazotization followed by coupling …

In this study, we have synthesized and studied de novo tyrosinase inhibitor, MHY1556,
which showed significantly better efficacy than other pre-existing tyrosinase inhibitors in vitro …

In the present paper, we report the synthesis and pharmacological evaluation of a new
series of azo compounds with different groups (1‐naphthol, 2‐naphthol, and N, N …

A series of novel 4-hydroxybenzaldehyde derivatives were synthesized and their inhibitory
effects on the diphenolase activity of mushroom tyrosinase were investigated. Most of target …

Tyrosinase is a key enzyme in melanin biosynthesis, and is also involved in the enzymatic
browning of plant-derived foods. Tyrosinase inhibitors are very important in medicine …

A series of alkylidenethiosemicarbazide compounds were synthesized and their inhibitory
effects on the diphenolase activity of mushroom tyrosinase were evaluated. The results …

Six new azo dyes containing of 5 (4H)-oxazolone ring were prepared by diazotization of 4-
aminohippuric acid and coupling with N, N-dimethylaniline, 1-naphthol and 2-naphthol and …

Abstract Tyrosinase (EC 1.14. 18.1) is a key copper-containing metalloenzyme widely
distributed in nature and plays determinant role in melanin biosynthesis. The enzyme …

Tyrosinase is a key enzyme in melanin synthesis, catalyzing the initial rate-limiting steps of
melanin synthesis. Abnormal and excessive melanin synthesis is the primary cause of …