Osteoarthritis (OA) is the most common degenerative joint disorder. OA was conceived as a
“wear and tear” problem of articular cartilage, yet there is a lack of treatment options to delay …

Osteoarthritis (OA) is characterized by irreversible destruction of the articular cartilage. OA
affects more than 100 million individuals worldwide and has a major impact on patients' …

Understanding biology at the systems level is a powerful method for discovery of previously
unrecognized molecular pathways and mechanisms in human disease. The application of …

The incidence of age-related musculoskeletal impairment is steadily rising throughout the
world. Musculoskeletal conditions are closely linked with aging and inflammation. They are …

Osteoarthritis (OA) is the most frequent rheumatic disease and is the leading cause of
disability in developed countries. Its poorly understood pathophysiology limits the discovery …

Introduction: Proteomic analyses have been acknowledged to carry a significant prospective
in elucidating the pathogenesis of several diseases, including osteoarthritis (OA). But it has …

Introduction 2.1. Articular cartilage 2.2. Osteoarthritis (OA) 2.3. The role of chondrocytes and
synoviocytes in the pathogenesis of OA 3. Proteomic approaches in cartilage biology and …

Osteoarthritis (OA) is the most common age-related degenerative joint disorder. It is
considered a disease of the entire joint, which is not simply a result of attrition but rather …

Proteomics is a growing field that offers insights into various aspects of disease processes
and therapy responses. Within the field of orthopedics, there are a variety of diseases that …

Purpose: The diagnosis methods currently available for Osteoarthritis (OA) are limited and
lack sensitivity. Therefore, there is a considerable interest pointed in identifying new specific …