Does adding lateral pelvic lymph node dissection to neoadjuvant chemotherapy improve outcomes in low rectal cancer?

BZY Law, Z Yusuf, YE Ng, EH Aly - International Journal of Colorectal …, 2020 - Springer
Purpose Lateral pelvic lymph node metastasis occurs in 15 to 20% of patients with locally
advanced low rectal cancer which increases risk of local recurrence and reduced survival …

[HTML][HTML] Lateral pelvic lymph node dissection after neoadjuvant chemo-radiation for preoperative enlarged lateral nodes in advanced low rectal cancer: study protocol …

M Wei, Q Wu, C Fan, Y Li, X Chen, Z Zhou, J Han… - Trials, 2016 - Springer
Background Lateral lymph node (LLN) metastasis is a major cause of local recurrence of
advanced rectal cancer. Although there is much controversy between Western and Eastern …

[HTML][HTML] Controversies in the management of lateral pelvic lymph nodes in patients with advanced rectal cancer: east or west?

J Otero de Pablos, J Mayol - Frontiers in Surgery, 2020 - frontiersin.org
The presence of lateral pelvic lymph nodes (LPLN) in advanced rectal cancer entails
challenges with ongoing debate regarding the role of prophylactic dissection vs …

[HTML][HTML] Lateral pelvic lymph node dissection after neoadjuvant chemoradiotherapy in patients with rectal cancer: a single-center experience and literature review

MC Kim, JH Oh - Annals of Coloproctology, 2021 - ncbi.nlm.nih.gov
Purpose We aimed to evaluate the surgicopathological outcomes of lateral pelvic lymph
node dissection (LPLD) and long-term oncological outcomes of selective LPLD after …

Who should get lateral pelvic lymph node dissection after neoadjuvant chemoradiation?

S Malakorn, Y Yang, BK Bednarski… - Diseases of the Colon …, 2019 - journals.lww.com
BACKGROUND: Despite the use of neoadjuvant chemoradiation and total mesorectal
excision for rectal cancer, lateral pelvic lymph node recurrence is still an important problem …

Lateral pelvic lymph node dissection in the management of locally advanced low rectal cancer: Summary of the current evidence

M Elhusseini, EH Aly - Surgical Oncology, 2020 - Elsevier
Lateral pelvic lymph nodes (LPLN) are a major site for local recurrence following curative
resection for low locally advanced rectal cancer. Ongoing advances in imaging techniques …

Lateral pelvic lymphadenectomy for low rectal cancer: a META-analysis of recurrence rates

MR Fahy, ME Kelly, T Nugent, E Hannan… - International Journal of …, 2021 - Springer
Background Locoregional recurrence (LR) remains a problem for patients with lower rectal
cancer despite standardized surgery and improved neoadjuvant treatment regimens. Lateral …

[HTML][HTML] Current perspectives on the management of lateral pelvic lymph nodes in rectal cancer

JYJ Chua, JCY Ngu, NZ Teo - World Journal of Clinical Oncology, 2023 - ncbi.nlm.nih.gov
Significant controversies exist with regards to the optimal management of lateral pelvic
lymph nodes metastases (mLLN) in patients with low rectal cancer. The differing views held …

Lateral lymph node dissection after neoadjuvant (chemo) radiotherapy may improve oncological outcomes in Western patients with low rectal cancer.

HM Kroon, S Malakorn, NN Dudi-Venkata… - 2020 - ascopubs.org
163 Background: In the West, rectal cancer patients with pre-treatment abnormal lateral
lymph nodes (LLN) are commonly treated with neoadjuvant (chemo) radiotherapy (n (C) RT) …

[HTML][HTML] Lateral lymph node dissection reduces local recurrence of locally advanced lower rectal cancer in the absence of preoperative neoadjuvant …

X Gao, C Wang, Y Yu, D Singh, L Yang… - World Journal of Surgical …, 2020 - Springer
Background The impact of lateral lymph node dissection (LLND) in locally advanced lower
rectal cancer remains controversial. This study is to compare total mesorectal excision (TME) …