We read with great interest the article by Wolfrum C, Challa TD et al., concerning “A low-
carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver …

Low-carbohydrate, high-fat ketogenic diets (KD) have been suggested to be more effective
in promoting weight loss than conventional caloric restriction, whereas their effect on hepatic …

Mice receiving a Western diet (WD) for 16 weeks were insulin resistant and developed
steatohepatitis with fibrosis (Figs 1-3). Switching these mice to a KD for further 8 weeks …

Non-alcoholic fatty liver disease (NAFLD) is one of the many clinical consequences of
obesity and increases one's risk of developing diabetes 5-fold, and is present in up to 2/3 of …

In this issue of the journal, Brandt et al.[1] report the effect of substituting a butterfat diet with
rapeseed oil (RO) on the progression of non-alcoholic fatty liver disease (NAFLD) and …

Obesity‐associated insulin resistance plays a major role in the pathogenesis of non‐
alcoholic fatty liver disease (NAFLD). The accumulation of diacylglycerol (DAG), ceramides …

Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common chronic
liver disease. Ketogenic diet (KD), a diet with very low intake in carbohydrates, gained …

Objective: The ketone diester, R, S-1, 3-butanediol diacetoacetate (BD-AcAc2), attenuates
the accretion of adiposity and reduces hepatic steatosis in high-fat diet-induced obese mice …

Key points A ketogenic diet is known to lead to weight loss and is considered metabolically
healthy; however there are conflicting reports on its effect on hepatic insulin sensitivity. KD …

Objectives Metabolic-associated fatty liver disease (MAFLD) is the most common chronic
liver disease that can range from hepatic steatosis to non-alcoholic steatohepatitis (NASH) …