Highlights (AQPs) are transmembrane proteins responsible for fast water movement across
cell membranes, including those of astrocytes. The expression and subcellular localization …

The family of aquaporins (AQPs), membrane water channels, consists of diverse types of
proteins that are mainly permeable to water; some are also permeable to small solutes, such …

Aquaporins (AQPs) mediate water flux between the four distinct water compartments in the
central nervous system (CNS). In the present chapter, we mainly focus on the expression …

Water movement plays vital roles in both physiological and pathological conditions in the
brain. Astrocytes are responsible for regulating this water movement and are the major …

Aquaporins (AQP) constitute an evolutionarily conserved family of integral membrane water
transport channel proteins. Previous studies indicate that AQP1 is expressed exclusively in …

Water homeostasis of the nervous system is important during neural signal transduction.
Astrocytes are crucial in water transport in the central nervous system under both …

Water homeostasis in the brain is of central physiologic and clinical importance. Neuronal
activity and ion water homeostasis are inextricably coupled. For example, the clearance of …

Aquaporin-4 (AQP4) is the major water channel in the CNS. Its expression at fluid-tissue
barriers (blood–brain and brain–cerebrospinal fluid barriers) throughout the brain and spinal …

The aquaporin (AQP) family of water channels are a group of small, membrane-spanning
proteins that are vital for the rapid transport of water across the plasma membrane. These …

Aquaporins (AQPs) are a family of water-selective channels that provide a major pathway for
osmotically driven water transport through cell membranes. Some members of the …