[图书][B] Amiodarone-induced pulmonary toxicity in F344 rats
MD Taylor - 2001 - search.proquest.com
Amiodarone (AD) is gaining support as a first-line antiarrhythmic drug despite its potentially
fatal pulmonary toxicity involving inflammation and fibrosis. The goals of this study were to …
fatal pulmonary toxicity involving inflammation and fibrosis. The goals of this study were to …
Intratracheal amiodarone administration to F344 rats directly damages lung airway and parenchymal cells
Amiodarone (AD) is gaining support as a first-line antiarrhythmic drug despite its potentially
fatal pulmonary toxicity involving inflammation and fibrosis. We previously reported a model …
fatal pulmonary toxicity involving inflammation and fibrosis. We previously reported a model …
Acute pulmonary inflammation in hamsters following intratracheal administration of amiodarone
TL Blake, MJ Reasor - Inflammation, 1995 - Springer
The use of the antiarrythmic drug amiodarone (AD) has been limited by the propensity of the
drug to cause severe lung damage. AD has been shown to produce a transient pulmonary …
drug to cause severe lung damage. AD has been shown to produce a transient pulmonary …
Investigation of the mechanism of amiodarone-induced pulmonary toxicity.
RG Leeder - 1996 - elibrary.ru
Amiodarone (AM) is an effective antidysrhythmic agent, restricted in use by the development
of pulmonary toxicity. An animal model of fibrosis resulting from systemic AM administration …
of pulmonary toxicity. An animal model of fibrosis resulting from systemic AM administration …
Amiodarone-induced pulmonary inflammation
BD Wilson, CE Clarkson, ML Lippmann - Am Rev Respir Dis, 1991 - atsjournals.org
Toinvestigate the hypotheses that amiodarone-induced pulmonary inflammation may be
related to direct drug toxicity, groups of 10or more Wistar rats were fed amiodarone by …
related to direct drug toxicity, groups of 10or more Wistar rats were fed amiodarone by …
A characterization of amiodarone-induced pulmonary toxicity in F344 rats and identification of surfactant protein-D as a potential biomarker for the development of the …
MD Taylor, K Van Dyke, LL Bowman, PR Miles… - Toxicology and applied …, 2000 - Elsevier
Amiodarone (AD) is gaining support as a first-line antiarrhythmic drug despite its potentially
fatal pulmonary toxicity involving inflammation and fibrosis. The goals of this study were to …
fatal pulmonary toxicity involving inflammation and fibrosis. The goals of this study were to …
Comparison of the in vivo pulmonary toxicity of amiodarone and des-oxo-amiodarone in the hamster
E Rafeiro, RG Leeder, JF Brien, GW Kabalka… - Toxicology and applied …, 1994 - Elsevier
Amiodarone (AM) is an effective antidysrhythmic agent, the use of which is limited because
of the drug′ s potential for causing life-threatening pulmonary fibrosis. Oxidative stress …
of the drug′ s potential for causing life-threatening pulmonary fibrosis. Oxidative stress …
Pulmonary responses to amiodarone in hamsters: comparison of intratracheal and oral administrations
TL Blake, MJ Reasor - Toxicology and applied pharmacology, 1995 - Elsevier
Amiodarone (AD) has been shown to produce a transient pulmonary fibrosis in hamsters
after intratracheal (it) instillation. The goal of this study was to examine bronchoalveolar …
after intratracheal (it) instillation. The goal of this study was to examine bronchoalveolar …
Amiodarone-induced pulmonary toxicity in Fischer rats: release of tumor necrosis factor alpha and transforming growth factor beta by pulmonary alveolar …
PG Reinhart, CG Gairola - Journal of toxicology and environmental …, 1997 - Taylor & Francis
Amiodarone is an antiarrhythmic drug with numerous side effects, the most serious being the
development of pulmonary toxicity. We have previously reported that a single intratra cheal …
development of pulmonary toxicity. We have previously reported that a single intratra cheal …
[图书][B] An investigation of mechanisms in the pathogenesis of amiodarone-induced pulmonary toxicity.
E Rafeiro - 1998 - library-archives.canada.ca
Amiodarone (AM) is an efficacious antidysrhythmic agent. However, its clinical use is limited
by life-threatening pulmonary toxicity. The morphological effects of AM on cultured lung …
by life-threatening pulmonary toxicity. The morphological effects of AM on cultured lung …