Reduction of amiodarone pulmonary toxicity in patients treated with angiotensin converting enzyme inhibitors and angiotensin receptor blockers
PURPOSE: Amiodarone is a widely used anti-arrhythmic medication. Its utility is, however,
limited by adverse side effects. The mechanism of amiodarone toxicity in the lungs is …
limited by adverse side effects. The mechanism of amiodarone toxicity in the lungs is …
Effect of long-term administration of amiodarone on rat lung and the possible protective role of vitamin E: a histological and immunohistochemical study
RA Zidan - Egyptian Journal of Histology, 2011 - journals.lww.com
Objective This study was undertaken to investigate the effect of long-term amiodarone
administration and withdrawal on the histological structure of rat lung. In addition, the …
administration and withdrawal on the histological structure of rat lung. In addition, the …
Effects of dietary vitamin E supplementation on pulmonary morphology and collagen deposition in amiodarone-and vehicle-treated hamsters
JW Card, RG Leeder, WJ Racz, JF Brien, TM Bray… - Toxicology, 1999 - Elsevier
Amiodarone (AM) is a potent antidysrhythmic agent that is limited in clinical use by its
adverse effects, including potentially life-threatening AM-induced pulmonary toxicity (AIPT) …
adverse effects, including potentially life-threatening AM-induced pulmonary toxicity (AIPT) …
[引用][C] Amiodarone-lnduced Injury of Human Pulmonary Artery Endothelial Cells: Protection by a-Tocopherol1
DL KACHEL, TP MOVER, WJ MARTIN II - the journal of pharmacology, 1990
Amiodarone-induced disruption of hamster lung and liver mitochondrial function: lack of association with thiobarbituric acid-reactive substance production
JW Card, BR Lalonde, E Rafeiro, AS Tam, WJ Racz… - Toxicology letters, 1998 - Elsevier
Amiodarone (AM) is an efficacious antidysrhythmic agent that is limited clinically by
numerous adverse effects. Of greatest concern is AM-induced pulmonary toxicity (AIPT) due …
numerous adverse effects. Of greatest concern is AM-induced pulmonary toxicity (AIPT) due …
Tissue drug accumulation and ultrastructural changes during amiodarone administration in rats
R Kannan, JSM Sarma, M Guha… - Toxicological …, 1989 - academic.oup.com
Pulmonary and hepatotoxicity arc the two major side effects of chronic amiodarone therapy.
We studied the accumulation of amiodarone and its principal metabolite …
We studied the accumulation of amiodarone and its principal metabolite …
Amiodarone pulmonary toxicity
ED Chan, TE King - 2007 - uptodate.com
Pulmonary toxicity is among the most serious adverse effects of amiodarone [1]. Several
forms of pulmonary disease occur among patients treated with amiodarone, including …
forms of pulmonary disease occur among patients treated with amiodarone, including …
Amiodarone causes decreased cell-mediated immune responses and inhibits the phospholipase C signaling pathway
BD Wilson, CE Clarkson, ML Lippmann - Lung, 1993 - Springer
Amiodarone can cause pulmonary toxicity along with an increase in phospholipid in
macrophages, lymphocytes, and other cell types. Phospholipid accumulates because …
macrophages, lymphocytes, and other cell types. Phospholipid accumulates because …
Clinical features of amiodarone-induced pulmonary toxicity.
RE Dusman, MS Stanton, WM Miles, LS Klein… - Circulation, 1990 - Am Heart Assoc
The incidence and clinical predictors of amiodarone pulmonary toxicity were examined in
573 patients treated with amiodarone for recurrent ventricular (456 patients) or …
573 patients treated with amiodarone for recurrent ventricular (456 patients) or …
Amiodarone-Induced Lung Toxicity: A Case Initially Not Correctly Framed
SM Umberto Sr, S Giovanni, PU Romeo… - Cureus, 2023 - search.proquest.com
Amiodarone-induced pulmonary toxicity (AIPT) is one of the most serious adverse effects of
amiodarone and is one of the leading causes of death associated with its use. The onset of …
amiodarone and is one of the leading causes of death associated with its use. The onset of …