[HTML][HTML] Anti-inflammatory effect of Tauroursodeoxycholic acid in RAW 264.7 macrophages, Bone marrow-derived macrophages, BV2 microglial cells, and spinal cord …

SJ Kim, WK Ko, MJ Jo, Y Arai, H Choi, H Kumar… - Scientific reports, 2018 - nature.com
This study aimed to investigate the anti-inflammatory effects of tauroursodeoxycholic acid
(TUDCA) after spinal cord injury (SCI) in rats. We induced an inflammatory process in RAW …

Ursodeoxycholic acid inhibits inflammatory responses and promotes functional recovery after spinal cord injury in rats

WK Ko, SJ Kim, MJ Jo, H Choi, D Lee, IK Kwon… - Molecular …, 2019 - Springer
The aim of this study was to investigate the anti-inflammatory effects by ursodeoxycholic acid
(UDCA) in rats with a spinal cord injury (SCI). A moderate mechanical compression injury …

[HTML][HTML] Anti-inflammatory effects of ursodeoxycholic acid by lipopolysaccharide-stimulated inflammatory responses in RAW 264.7 macrophages

WK Ko, SH Lee, SJ Kim, MJ Jo, H Kumar, IB Han… - PLoS …, 2017 - journals.plos.org
Purpose The aim of this study was to investigate the anti-inflammatory effects of
Ursodeoxycholic acid (UDCA) in lipopolysaccharide (LPS)-stimulated RAW 264.7 …

[HTML][HTML] Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response

Y Hou, J Luan, T Huang, T Deng, X Li, Z Xiao… - Journal of …, 2021 - Springer
Background Tauroursodeoxycholic acid (TUDCA) is a hydrophilic bile acid derivative, which
has been demonstrated to have neuroprotective effects in different neurological disease …

[HTML][HTML] Neuroprotective effects and impact on caspase-12 expression of tauroursodeoxycholic acid after acute spinal cord injury in rats

Y Dong, L Miao, L Hei, L Lin, H Ding - International journal of …, 2015 - ncbi.nlm.nih.gov
Objective: To observe the effects of tauroursodeoxycholic acid (TUDCA) on nerve function
after acute spinal cord injury (SCI) in rats, observe its effect on neuronal apoptosis and …

Transplantation of tauroursodeoxycholic acid–inducing M2‐phenotype macrophages promotes an anti‐neuroinflammatory effect and functional recovery after spinal …

GH Han, SJ Kim, WK Ko, D Lee, IB Han… - Cell …, 2021 - Wiley Online Library
Objectives In this study, we study the transplantation of tauroursodeoxycholic acid (TUDCA)‐
induced M2‐phenotype (M2) macrophages and their ability to promote anti …

[HTML][HTML] Mechanism of tauroursodeoxycholic acid-mediated neuronal protection after acute spinal cord injury through AKT signaling pathway in rats

Y Dong, S Yang, B Fu, F Liu, S Zhou… - … Journal Of Clinical …, 2020 - ncbi.nlm.nih.gov
Objective: To explore themechanism of tauroursodeoxycholic acid-(TUDCA) mediated
neuronal protection after acute spinal cord injury (ASCI) in rats. Methods: ASCI rat model …

Injectable hydrogel containing tauroursodeoxycholic acid for anti-neuroinflammatory therapy after spinal cord injury in rats

GH Han, SJ Kim, WK Ko, D Lee, JS Lee, H Nah… - Molecular …, 2020 - Springer
We investigate the anti-inflammatory effects of injectable hydrogel containing
tauroursodeoxycholic acid (TUDCA) in a spinal cord injury (SCI) model. To this end, TUDCA …

[PDF][PDF] Protective effect of tauroursodeoxycholic acid on the autophagy of nerve cells in rats with acute spinal cord injury.

L Miao, Y Dong, FB Zhou, YL Chang… - European Review for …, 2018 - europeanreview.org
OBJECTIVE: To investigate the impact and protective effect of tauroursodeoxycholic acid
(TUDCA) on the autophagy of nerve cells in rats with acute spinal cord injury. MATERIALS …

Tauroursodeoxycholic acid ameliorates lipopolysaccharide-induced depression like behavior in mice via the inhibition of neuroinflammation and oxido-nitrosative …

L Cheng, C Huang, Z Chen - Pharmacology, 2019 - karger.com
Depression is a mental disease that causes severe economic and social burdens. The
mechanism for the onset of depression remains largely unknown. Recently, more and more …