[HTML][HTML] Vascular endothelial growth factor (VEGF) bioavailability regulates angiogenesis and intestinal stem and progenitor cell proliferation during postnatal small …

CR Schlieve, SG Mojica, KA Holoyda, X Hou… - PloS one, 2016 - journals.plos.org
Background Vascular endothelial growth factor (VEGF) is a highly conserved, master
regulatory molecule required for endothelial cell proliferation, organization, migration and …

[HTML][HTML] Vegfa signaling promotes zebrafish intestinal vasculature development through endothelial cell migration from the posterior cardinal vein

AL Koenig, K Baltrunaite, NI Bower, A Rossi… - Developmental …, 2016 - Elsevier
The mechanisms underlying organ vascularization are not well understood. The zebrafish
intestinal vasculature forms early, is easily imaged using transgenic lines and in-situ …

Vegfc is required for vascular development and endoderm morphogenesis in zebrafish

EA Ober, B Olofsson, T Mäkinen, SW Jin, W Shoji… - EMBO …, 2004 - embopress.org
During embryogenesis, complex morphogenetic events lead endodermal cells to coalesce
at the midline and form the primitive gut tube and associated organs. While several genes …

Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic development

NI Bower, AJ Vogrin, L Le Guen, H Chen… - …, 2017 - journals.biologists.com
Vascular endothelial growth factors (VEGFs) control angiogenesis and lymphangiogenesis
during development and in pathological conditions. In the zebrafish trunk, Vegfa controls the …

[HTML][HTML] Vegf signaling promotes vascular endothelial differentiation by modulating etv2 expression

SC Chetty, MS Rost, JR Enriquez, JA Schumacher… - Developmental …, 2017 - Elsevier
Vasculogenesis involves the differentiation of vascular endothelial progenitors de novo from
undifferentiated mesoderm, their migration and coalescence to form the major embryonic …

Transgenic expression of VEGF in intestinal epithelium drives mesenchymal cell interactions and epithelial neoplasia

A Boquoi, R Jover, T Chen, M Pennings, GH Enders - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Vascular endothelial growth factor (VEGF) is expressed robustly in
human colon neoplasia and is a major new “rational” target of therapy for cancers of the …

Lack of VEGFR2 signaling causes maldevelopment of the intestinal microvasculature and facilitates necrotizing enterocolitis in neonatal mice

X Yan, E Managlia, SXL Liu, XD Tan… - American Journal …, 2016 - journals.physiology.org
The pathogenesis of necrotizing enterocolitis (NEC), a common gastrointestinal disease
affecting premature infants, remains poorly understood. We previously found that intestinal …

VEGF regulates cell behavior during vasculogenesis

CJ Drake, A LaRue, N Ferrara, CD Little - Developmental biology, 2000 - Elsevier
Prominent among molecules that control neovascular processes is vascular endothelial
growth factor (VEGF). The VEGF ligands comprise a family of well-studied …

A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development

JA Villefranc, S Nicoli, K Bentley, M Jeltsch… - …, 2013 - journals.biologists.com
Vascular endothelial growth factor C (Vegfc) is a secreted protein that guides lymphatic
development in vertebrate embryos. However, its role during developmental angiogenesis is …

Interplay of vascular endothelial growth factor receptors in organ-specific vessel maintenance

S Karaman, S Paavonsalo, K Heinolainen… - Journal of Experimental …, 2022 - rupress.org
Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are
quintessential for the development and maintenance of blood and lymphatic vessels …