Insulin in amyotrophic lateral sclerosis: impairment, tests and treatment
A Rappoport - 2023 - preprints.org
Background. Amyotrophic Lateral Sclerosis (ALS) is a devastating disease involving motor
neuron degeneration. The few drugs approved for treatment have at most a marginal benefit …
neuron degeneration. The few drugs approved for treatment have at most a marginal benefit …
[PDF][PDF] Insulin-Based Treatment for Amyotrophic Lateral Sclerosis
A Rappoport - 2022 - scholar.archive.org
Abstract Background. Amyotrophic Lateral Sclerosis (ALS) is a devastating disease
involving motor neuron degeneration. The few drugs approved for treatment have at most a …
involving motor neuron degeneration. The few drugs approved for treatment have at most a …
ALSUntangled# 72: Insulin
A Brown, C Armon, P Barkhaus… - … Lateral Sclerosis and …, 2024 - Taylor & Francis
ALSUntangled reviews alternative and off-label treatments for people living with
amyotrophic lateral sclerosis (PALS). Here we review insulin, which has at least one …
amyotrophic lateral sclerosis (PALS). Here we review insulin, which has at least one …
Trials of antidiabetic drugs in amyotrophic lateral sclerosis: proceed with caution?
A Jawaid, S Paganoni, C Hauser… - Neurodegenerative …, 2014 - karger.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with limited
therapeutic options. Clinical trials of several drugs shown to be effective in the superoxide …
therapeutic options. Clinical trials of several drugs shown to be effective in the superoxide …
ALS disease onset may occur later in patients with pre‐morbid diabetes mellitus
A Jawaid, AR Salamone, AM Strutt… - European Journal of …, 2010 - Wiley Online Library
Background Several metabolic derangements associated with diabetes mellitus type 2 (DM)
have been associated with a better outcome in amyotrophic lateral sclerosis (ALS), including …
have been associated with a better outcome in amyotrophic lateral sclerosis (ALS), including …
Impaired glucose tolerance in patients with amyotrophic lateral sclerosis
PF Pradat, G Bruneteau, PH Gordon… - Amyotrophic Lateral …, 2010 - Taylor & Francis
Our objectives were to analyse carbohydrate metabolism in a series of ALS patients and to
examine potential association with parameters of lipid metabolism and clinical features …
examine potential association with parameters of lipid metabolism and clinical features …
Reduction in insulin receptors in amyotrophic lateral sclerosis correlates with reduced insulin sensitivity
OH Perurena, BW Festoff - Neurology, 1987 - AAN Enterprises
Abnormal glucose and insulin metabolism have often been reported in patients with
amyotrophic lateral sclerosis. Recently, we have demonstrated reduced insulin sensitivity in …
amyotrophic lateral sclerosis. Recently, we have demonstrated reduced insulin sensitivity in …
Diabetes mellitus and amyotrophic lateral sclerosis: a systematic review
L Ferri, P Ajdinaj, MG Rispoli, C Carrarini, F Barbone… - Biomolecules, 2021 - mdpi.com
Background: Amyotrophic Lateral Sclerosis (ALS) is a degenerative disorder which affects
the motor neurons. Growing evidence suggests that ALS may impact the metabolic system …
the motor neurons. Growing evidence suggests that ALS may impact the metabolic system …
Diabetes mellitus, obesity, and diagnosis of amyotrophic lateral sclerosis: a population-based study
MA Kioumourtzoglou, RS Rotem, RM Seals… - JAMA …, 2015 - jamanetwork.com
Importance Although prior studies have suggested a role of cardiometabolic health on
pathogenesis of amyotrophic lateral sclerosis (ALS), the association with diabetes mellitus …
pathogenesis of amyotrophic lateral sclerosis (ALS), the association with diabetes mellitus …
Effects of diabetes mellitus on amyotrophic lateral sclerosis: a systematic review
A Lekoubou, TE Matsha, E Sobngwi, AP Kengne - BMC research notes, 2014 - Springer
Background Amyotrophic lateral sclerosis (ALS) is an incurable motor neuron degenerative
disease which onset and course may be affected by concurrent diabetes mellitus (DM). We …
disease which onset and course may be affected by concurrent diabetes mellitus (DM). We …