Mechanisms of testicular torsion and potential protective agents

E Karaguzel, M Kadihasanoglu, O Kutlu - Nature Reviews Urology, 2014 - nature.com
Testicular torsion is a urological emergency most commonly seen in adolescence, involving
a decrease in blood flow in the testis resulting from torsion of the spermatic cord that can …

Testicular torsion–detorsion and potential therapeutic treatments: A possible role for ischemic postconditioning

S Shimizu, P Tsounapi, F Dimitriadis… - … Journal of Urology, 2016 - Wiley Online Library
Testicular torsion is a common urological emergency among adolescent boys and young
men. Rotation of the testis and twisting of the spermatic cord rapidly leads to ischemia …

Molecular pathways involved in the early and late damage induced by testis ischemia: evidence for a rational pharmacological modulation

D Altavilla, C Romeo, F Squadrito… - Current medicinal …, 2012 - ingentaconnect.com
Testicular torsion or torsion of the spermatic cord is a surgical emergency in which
misdiagnosis and inappropriate treatment can lead to male infertility. Events occurring …

The molecular pathology of experimental testicular torsion suggests adjunct therapy to surgical repair

TT Turner, HJ Bang, JL Lysiak - The Journal of urology, 2004 - auajournals.org
Purpose: We review the work of our laboratory in discovering the pathophysiological
mechanisms that underpin testicular response to testicular torsion. Evidence from animal …

Rescue of testicular function after acute experimental torsion

HM Prillaman, TT Turner - The Journal of urology, 1997 - auajournals.org
Purpose: Spermatic cord torsion results in impairment of testicular function. The mechanism
of this injury is unclear; however, intracellular Ca sup++ influx and reactive oxygen species …

Reperfusion injury following testicular torsion and detorsion in prepubertal rats

ML Blank, PJ O'Neill, CK Steigman, LM Cobb… - Urological …, 1993 - Springer
Acute testicular torsion is a surgical emergency which requires immediate intervention.
Although damage to the gonad has been well documented, it remains unknown whether the …

[HTML][HTML] The impact of testicular torsion on testicular function

FM Jacobsen, TM Rudlang, M Fode… - The world journal of …, 2020 - ncbi.nlm.nih.gov
Torsion of the spermatic cord is a urological emergency that must be treated with acute
surgery. Possible long-term effects of torsion on testicular function are controversial. This …

Ischemic preconditioning and post-conditioning to decrease testicular torsion-detorsion injury

S Shimizu, M Saito, Y Kinoshita, K Shomori, I Satoh… - The Journal of …, 2009 - Elsevier
PURPOSE: The main pathophysiology of torsion-detorsion is associated with ischemia-
reperfusion injury in the testis caused by the twisted spermatic cord and its release. It is most …

[HTML][HTML] Medical perspective in testicular ischemia‑reperfusion injury

S Arena, R Iacona, P Antonuccio… - Experimental and …, 2017 - spandidos-publications.com
Testicular torsion or torsion of the spermatic cord is one of the most serious urological
conditions. It causes testicular injury, which potentially leads to male subfertility. The turning …

Experimental testicular torsion: reperfusion blood flow and subsequent testicular venous plasma testosterone concentrations

TT Turner, HJ Bang, JJ Lysiak - Urology, 2005 - Elsevier
OBJECTIVES: To examine the effect of torsion on subsequent testicular venous plasma
testosterone concentrations (TVT) and to determine the relationship between the TVT values …