Very few of the genes that are important in pituitary tumor initiation, progression, and
metastasis have been identified to date. To identify potential genes that may be important in …

Pituitary adenomas account for approximately 10% of intracranial tumors, but little is known
of the oncogenesis of these tumors. The identification of tumor-specific genes may further …

Objectives Microarray technology allows for the expression profile of many thousands of
genes to be quantified at the same time, and has resulted in novel discoveries about the …

Pituitary tumours are common intracranial neoplasms that cause significant morbidity
through mass effects and/or the inappropriate secretion of pituitary hormones. Despite a …

Pituitary adenomas comprise 10% of intracranial tumors and occur in about 20% of the
population. They cause significant morbidity by compression of regional structures or the …

Predicting pituitary tumor behavior remains a challenge, since the prognostic value of
identified pathological markers has not yet been evaluated. Genome-wide transcriptome …

Although most pituitary tumors are benign, some are invasive or aggressive. In the absence
of specific markers of malignancy, only tumors with metastases are considered malignant …

Substantial advances have been made recently in the pathobiology of pituitary tumors.
Similar to many other endocrine tumors, over the last few years we have recognized the role …

Aging of the rat pituitary is often accompanied by the occurrence of adenomas. We asked
whether complementary DNA hybridization array was adapted to identify gene expression …

Many new techniques are rapidly being developed and applied to the study of normal and
neoplastic pituitary. DNA microarrays are a uniquely efficient method for simultaneously …