Tomographic phase microscopy

W Choi, C Fang-Yen, K Badizadegan, S Oh, N Lue… - Nature …, 2007 - nature.com
We report a technique for quantitative three-dimensional (3D) mapping of refractive index in
live cells and tissues using a phase-shifting laser interferometric microscope with variable …

Cell refractive index for cell biology and disease diagnosis: past, present and future

PY Liu, LK Chin, W Ser, HF Chen, CM Hsieh, CH Lee… - Lab on a Chip, 2016 - pubs.rsc.org
Cell refractive index is a key biophysical parameter, which has been extensively studied. It is
correlated with other cell biophysical properties including mechanical, electrical and optical …

Spatial light interference microscopy and fourier transform light scattering for cell and tissue characterization

G Popescu, Z Wang - US Patent 8,184,298, 2012 - Google Patents
Popescu, G.,“Quantitative phase imaging and applications. a review.” pp. 1-32, Oct. 5, 2006,
retrieved on May 2, 2008). Retrieved from the Internet:< URL: http://light. ece. uiuc. edu/OPI …

In vivo endoscopic tissue diagnostics based on spectroscopic absorption, scattering, and phase function properties

P Thueler, I Charvet, F Bevilacqua… - … of biomedical optics, 2003 - spiedigitallibrary.org
A fast spectroscopic system for superficial and local determination of the absorption and
scattering properties of tissue (480 to 950 nm) is described. The probe can be used in the …

Partial-wave microscopic spectroscopy detects subwavelength refractive index fluctuations: an application to cancer diagnosis

H Subramanian, P Pradhan, Y Liu, IR Capoglu… - Optics letters, 2009 - opg.optica.org
Existing optical imaging techniques offer us powerful tools to directly visualize the cellular
structure at the microscale; however, their capability of nanoscale sensitivity is restricted by …

Dynamic quantitative phase imaging for biological objects using a pixelated phase mask

K Creath, G Goldstein - Biomedical optics express, 2012 - opg.optica.org
This paper describes research in developing a dynamic quantitative phase imaging
microscope providing instantaneous measurements of dynamic motions within and among …

Full-field optical coherence microscopy for identifying live cancer cells by quantitative measurement of refractive index distribution

WJ Choi, DI Jeon, SG Ahn, JH Yoon, S Kim, BH Lee - Optics express, 2010 - opg.optica.org
The feasibility of identifying cancer cells by measuring the refractive index (RI) distribution
across a single live cell with ultrahigh resolution full-field optical coherence microscopy (FF …

Epi-mode tomographic quantitative phase imaging in thick scattering samples

P Ledwig, FE Robles - Biomedical optics express, 2019 - opg.optica.org
Quantitative phase imaging (QPI) is an important tool in biomedicine that allows for the
microscopic investigation of live cells and other thin, transparent samples. Importantly, this …

Perspective: Wavefront shaping techniques for controlling multiple light scattering in biological tissues: Toward in vivo applications

JH Park, Z Yu, KR Lee, P Lai, YK Park - APL photonics, 2018 - pubs.aip.org
Light scattering is a fundamental physical phenomenon and also plays critical roles in
optical imaging. To optically visualize an object, waves scattered from individual positions in …

Analysis of changes in reflectance measurements on biological tissues subjected to different probe pressures

R Reif, MS Amorosino, KW Calabro… - … of biomedical optics, 2008 - spiedigitallibrary.org
Spectral reflectance measurements of biological tissues have been studied for early
diagnoses of several pathologies such as cancer. These measurements are often performed …