Light scattering is a fundamental physical phenomenon and also plays critical roles in
optical imaging. To optically visualize an object, waves scattered from individual positions in …

Spectral reflectance measurements of biological tissues have been studied for early
diagnoses of several pathologies such as cancer. These measurements are often performed …

To complement a project towards the development of real-time optical biopsy for brain tissue
discrimination and surgical resection guidance, the optical properties of various brain …

Significance: We introduce an application of machine learning trained on optical phase
features of epithelial and mesenchymal cells to grade cancer cells' morphologies, relevant to …

Optical microscopy is an indispensable diagnostic tool in modern healthcare. As a prime
example, pathologists rely exclusively on light microscopy to investigate tissue morphology …

Here, we present a novel microscopic technique for measuring wavelength-dependent three-
dimensional (3-D) distributions of the refractive indices (RIs) of microscopic samples in the …

We report the experimental implementation of optical diffraction tomography for quantitative
3D mapping of refractive index in live biological cells. Using a heterodyne Mach-Zehnder …

A simple method based on total internal reflection is presented for measuring the refractive
index of biological tissue. A narrow laser beam and a semicylindrical lens in contact with a …

Intensity diffraction tomography (IDT) provides quantitative, volumetric refractive index
reconstructions of unlabeled biological samples from intensity-only measurements. IDT is …

Background Using optical techniques for tissue diagnostics (so-called 'optical biopsy') has
been a subject of extensive research for many years. Various groups have been exploring …