Standardizing gc–ms metabolomics

H Kanani, PK Chrysanthopoulos, MI Klapa - Journal of Chromatography B, 2008 - Elsevier
Metabolomics being the most recently introduced “omic” analytical platform is currently at its
development phase. For the metabolomics to be broadly deployed to biological and clinical …

Review of recent developments in GC–MS approaches to metabolomics-based research

DJ Beale, FR Pinu, KA Kouremenos, MM Poojary… - Metabolomics, 2018 - Springer
Background Metabolomics aims to identify the changes in endogenous metabolites of
biological systems in response to intrinsic and extrinsic factors. This is accomplished …

Untargeted GC-MS Metabolomics

MEP Papadimitropoulos, CG Vasilopoulou… - … profiling: Methods and …, 2018 - Springer
Untargeted metabolomics refers to the high-throughput analysis of the metabolic state of a
biological system (eg, tissue, biological fluid, cell culture) based on the concentration profile …

[HTML][HTML] Quantitative metabolomics based on gas chromatography mass spectrometry: status and perspectives

MM Koek, RH Jellema, J van der Greef, AC Tas… - Metabolomics, 2011 - Springer
Metabolomics involves the unbiased quantitative and qualitative analysis of the complete set
of metabolites present in cells, body fluids and tissues (the metabolome). By analyzing …

Integration of GC–MS and LC–MS for untargeted metabolomics profiling

ÖC Zeki, CC Eylem, T Reçber, S Kır… - Journal of Pharmaceutical …, 2020 - Elsevier
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …

metaMS: An open-source pipeline for GC–MS-based untargeted metabolomics

R Wehrens, G Weingart, F Mattivi - Journal of Chromatography B, 2014 - Elsevier
Untargeted metabolomics are rapidly becoming an important tool for studying complex
biological samples. Gas chromatography–mass spectrometry (GC–MS) is the most widely …

Metabolomics by gas chromatography–mass spectrometry: Combined targeted and untargeted profiling

O Fiehn - Current protocols in molecular biology, 2016 - Wiley Online Library
Gas chromatography–mass spectrometry (GC‐MS)–based metabolomics is ideal for
identifying and quantitating small‐molecule metabolites (< 650 Da), including small acids …

Cross-platform comparison of methods for quantitative metabolomics of primary metabolism

JM Büscher, D Czernik, JC Ewald, U Sauer… - Analytical …, 2009 - ACS Publications
Quantitative metabolomics is under intense development, and no commonly accepted
standard analytical technique has emerged, yet. The employed analytical methods were …

High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses

P Jonsson, AI Johansson, J Gullberg, J Trygg… - Analytical …, 2005 - ACS Publications
In metabolomics, the objective is to identify differences in metabolite profiles between
samples. A widely used tool in metabolomics investigations is gas chromatography− mass …

Gas chromatography-mass spectrometry (GC-MS)-based metabolomics

A Garcia, C Barbas - Metabolic profiling: Methods and protocols, 2011 - Springer
Metabolic fingerprinting, the main tool in metabolomics, is a non-targeted methodology
where all detectable peaks (or signals), including those from unknown analytes, are …