Lower expression of CD81 B‐cell receptor in lymphoproliferative diseases associated with hepatitis C virus infection

P Cacoub, M Bourliere, P Hausfater… - Journal of Viral …, 2003 - Wiley Online Library
Chronic hepatitis C virus (HCV) infection is frequently associated with type II mixed
cryoglobulinaemia (MC), a benign lymphoproliferative disease (LPD). More recently, HCV …

Peripheral B-cell CD5 expansion and CD81 overexpression and their association with disease severity and autoimmune markers in chronic hepatitis C virus infection

E Zuckerman, G Slobodin, A Kessel… - Clinical & …, 2002 - academic.oup.com
Hepatitis C virus (HCV) infection is associated with immune-mediated abnormalities and B-
cell lymphoproliferation evolving to an overt lymphoma. Recently, CD81 was identified as an …

CD81 down-regulation on B cells is associated with the response to interferon-alpha-based treatment for chronic hepatitis C virus infection

LL Chang, PN Cheng, JS Chen, KC Young - Antiviral research, 2007 - Elsevier
The lymphocytic CD81 molecule, capable of modulating type-1/-2 T-helper responses and
serving as a putative receptor for hepatitis C virus (HCV), might influence the outcome of anti …

Expansion of CD5+ B-cell overexpressing CD81 in HCV infection: towards better understanding the link between HCV infection, B-cell activation and …

E Zuckerman - Journal of hepatology, 2003 - journal-of-hepatology.eu
Hepatitis C virus (HCV) infection is one of the major causes of chronic liver disease in the
Western world affecting 1.8% of the American population and 170 million people worldwide …

Antiviral treatment down-regulates peripheral B-cell CD81 expression and CD5 expansion in chronic hepatitis C virus infection

E Zuckerman, A Kessel, G Slobodin, E Sabo… - Journal of …, 2003 - Am Soc Microbiol
Hepatitis C virus (HCV) infection is associated with immune-mediated abnormalities and B-
cell lymphoproliferation. Recently, CD81 was identified as an HCV receptor on B …

CD81 expression on CD19+ peripheral blood lymphocytes is associated with chronic HCV disease and increased risk for HCV infection: a putative role for …

G D'Agosto, E Trento, L Nosotti… - Journal of Biological …, 2009 - europepmc.org
The level of CD81 cell surface expression, a cellular co-receptor for hepatitis C virus (HCV),
is critical for productive HCV infection of host cells. In addition, the cross-linking of HCV-E2 …

Lymphoproliferative diseases and hepatitis C virus infection.

P Hausfater, E Rosenthal, P Cacoub - Annales de Medecine Interne, 2000 - europepmc.org
The putative role of hepatitis C virus (HCV) infection in the pathophysiology of
lymphoproliferative diseases (LPD) is supported by north-American and south-European …

Expansion of innate CD5pos B cells expressing high levels of CD81 in hepatitis C virus infected liver

MP Curry, L Golden-Mason, DG Doherty, T Deignan… - Journal of …, 2003 - Elsevier
Background/Aims: Association of hepatitis C virus (HCV) with increased autoantibodies,
mixed cryoglobulinaemia, non-Hodgkin's B-cell lymphoma and increased peripheral innate …

Activation of naive B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders

D Rosa, G Saletti, E De Gregorio… - Proceedings of the …, 2005 - National Acad Sciences
Infection with hepatitis C virus (HCV), a leading cause of chronic liver diseases, can
associate with B lymphocyte proliferative disorders, such as mixed cryoglobulinemia and …

Dynamics of CD81 expression on lymphocyte subsets during interferon-α-based antiviral treatment of patients with chronic hepatitis C

B Kronenberger, E Herrmann… - Journal of leukocyte …, 2006 - academic.oup.com
CD81 is a hepatitis C virus (HCV) coreceptor with important functions in lymphocytes. During
treatment, CD81 expression may be changed directly by the antiviral therapy or indirectly by …