Cancer is among the leading causes of death worldwide. Therefore, improving cancer
therapeutic strategies using novel alternatives is a top priority on the contemporary scientific …

Adoptive cell therapy (ACT) has seen a steep rise of new therapeutic approaches in its
immune-oncology pipeline over the last years. This is in great part due to the recent …

Adaptive immunity, orchestrated by B-cells and T-cells, plays a crucial role in protecting the
body from pathogenic invaders and can be used as tools to enhance the body's defense …

The use of immunotherapy as an alternative treatment for cancer patients has become of
great interest in the scientific community as it is required to overcome many of the currently …

Immunotherapy has emerged as a crucial treatment option, particularly for types of cancer
that display resistance to conventional therapies. A remarkable breakthrough in this field is …

The immune system acting via cancer immune-surveillance is considered a potential target
for improving outcomes among some malignancies. The ability to harness immune cells …

Advances in immuno‐oncology have provided a variety of novel therapeutics that harness
the innate immune system to identify and destroy neoplastic cells. It is noteworthy that …

Immunotherapy represents the fourth pillar of cancer therapy after surgery, chemotherapy,
and radiation. Chimeric antigen receptor (CAR)-T-cell therapy is an artificial immune cell …

Chimeric antigen receptor (CAR) T-cell therapy was envisioned as a mechanism to re-direct
effector T-cells to eliminate tumor cells. CARs are composed of the variable region of an …

After seeing a dramatic increase in the development and use of immunotherapy and
precision medicine over the past few decades, oncological care now embraces the start of …