Expression of interleukin 2 receptors on human carcinoma cell lines and tumor growth inhibition by interleukin 2

S Yasumura, WC Lin, E Weidmann… - … journal of cancer, 1994 - Wiley Online Library
We have previously shown that human squamous cell carcinomas (SCC) express the
interleukin 2 receptor (IL2R)‐α and‐β chains, and that the ligand, IL2, directly inhibits growth …

Receptors for Interleukin 2 on Human Squamous Cell Carcinoma Cell Lines and Tumor in Situ

E Weidmann, M Sacchi, S Plaisance, DS Heo… - Cancer research, 1992 - AACR
Several human head and neck squamous carcinoma cell lines were found to bind 125I-
labeled or fluorescein-labeled interleukin 2 (IL-2). This binding was inhibited by an excess of …

Interleukin 2 receptor expression and interleukin 2 localisation in human solid tumour cells in situ and in vitro: Evidence for a direct role in the regulation of tumour …

DN McMillan, NM Kernohan, ME Flett… - … journal of cancer, 1995 - Wiley Online Library
Frozen sections of 52 human solid tumours (38 malignant and 14 benign) of varied
histogenesis were immunohistochemically stained with well characterised monoclonal …

Overexpression of interleukin‐2 receptor α in a human squamous cell carcinoma of the head and neck cell line is associated with increased proliferation, drug …

DJ Kuhn, DM Smith, S Pross… - Journal of cellular …, 2003 - Wiley Online Library
It has been previously demonstrated that human carcinomas express interleukin‐2 receptor
(IL‐2R) α, β, and γ chains. The β and γ chains of IL‐2R have intermediate binding affinity for …

Interleukin 4 receptor expression and growth inhibition of gastric carcinoma cells by interleukin 4

T Morisaki, DH Yuzuki, RT Lin, LJ Foshag, DL Morton… - Cancer research, 1992 - AACR
The expression of the interleukin 4 (IL-4) receptor (IL-4R) and effects of human recombinant
IL-4 on human gastric carcinoma cell lines were studied. We demonstrated that IL-4 …

Growth inhibition of human colorectal‐carcinoma cells by interleukin‐4 and expression of functional interleukin‐4 receptors

H Lahm, B Schnyder, J Wyniger… - … journal of cancer, 1994 - Wiley Online Library
The growth‐inhibitory effect of interleukin‐4 (IL‐4) was investigated in a panel of 7 human
colorectal‐carcinoma cell lines. In 5 cell lines (HT29, WiDr, LS41 IN, LS513, LS1034) a …

Altered expression of interleukin‐1 receptor antagonist in different stages of mouse skin carcinogenesis

E La, SJ Muga, MF Locniskar… - … in cooperation with the …, 1999 - Wiley Online Library
Abstract Interleukin‐1 receptor antagonist (IL‐1Ra) is an endogenous inhibitor of interleukin‐
1. The expression of IL‐1Ra and interleukin‐1α (IL‐1α) was measured in murine epidermis …

Head and neck cancers, but not benign lesions, express interleukin-4 receptors in situ.

R Mehrotra, F Varricchio, SR Husain… - Oncology …, 1998 - spandidos-publications.com
We have previously reported on the expression of interleukin-4 receptor (IL-4R) on many
solid cancer cell lines. In the present study, we have examined the expression of IL-4R on …

The role of endogenous interleukin-2 in proliferation of human carcinoma cell lines

TE Reichert, Y Kashii, J Stanson, A Zeevi… - British journal of …, 1999 - nature.com
Abstract Interleukin (IL-2) and IL-2Rβ/γ have been shown to be expressed in human
carcinomas in culture and in situ. Recently, expression of endogenous IL-2 and IL-2R in the …

Role of intracellular interleukin‐1 receptor antagonist in skin carcinogenesis

E La, JE Rundhaug, SM Fischer - … Carcinogenesis: Published in …, 2001 - Wiley Online Library
Abstract Interleukin 1 (IL‐1) is a major mediator of inflammation and exerts pleiotropic effects
on many systems. To elucidate the role of its endogenous inhibitor, intracellular IL‐1 …